TRIM9 and VASP

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM9	VASP
Gene Name		tripartite motif containing 9	vasodilator-stimulated phosphoprotein
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Synaptic Vesicle Cell Junction Dendrite	Cytoplasm Cytosol Plasma Membrane Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Protein Homodimerization Activity	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly T Cell Receptor Signaling Pathway Protein Homotetramerization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Cell junction organization TCR signaling Generation of second messenger molecules Axon guidance Signaling by Robo receptor Cell-extracellular matrix interactions Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 VASP	36 interactors: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP DMRTB1 DNMBP ERMAP FAT1 FGFR1OP FYB GSN LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX
Entrez ID		114088	7408
HPRD ID		05947	03415
Ensembl ID		ENSG00000100505	ENSG00000125753
Uniprot IDs		Q9C026	P50552
PDB IDs		2DB8	1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Organelle Organization Regulation Of Protein Stability Cellular Protein Metabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Regulation Of Viral Transcription Protein Complex Assembly Protein Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Release From Host Cell Regulation Of Circadian Rhythm Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Actin Filament Polymerization Cellular Macromolecule Catabolic Process Synaptic Vesicle Transport Anterograde Synaptic Vesicle Transport Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Viral Transcription Positive Regulation Of Proteolysis Regulation Of Viral Release From Host Cell Cellular Protein Catabolic Process Positive Regulation Of Protein Polymerization G2/M Transition Of Mitotic Cell Cycle Protein Destabilization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Catabolic Process Anterograde Axon Cargo Transport Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Viral Process Mitotic Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Positive Regulation Of Organelle Organization Circadian Rhythm Regulation Of Actin Filament Polymerization Organelle Localization Mitotic Cell Cycle Cellular Response To UV-C Cellular Response To Vitamin B1 Posttranscriptional Regulation Of Gene Expression Regulation Of Protein Metabolic Process Positive Regulation Of Cytoskeleton Organization Establishment Of Vesicle Localization	Actin Cytoskeleton Organization Actin Filament-based Process Cytoskeleton Organization Actin Filament Organization Movement Of Cell Or Subcellular Component Response To Wounding Organelle Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Polymerization Or Depolymerization Blood Coagulation Positive Regulation Of Actin Nucleation Wound Healing Hemostasis Platelet Activation Positive Regulation Of Cytoskeleton Organization Anatomical Structure Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Development Locomotion Negative Regulation Of Protein Complex Assembly Regulation Of Body Fluid Levels Regulation Of Actin Filament-based Process Negative Regulation Of Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cell Projection Organization Regulation Of Actin Nucleation Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Regulation Of Cellular Process Positive Regulation Of ATPase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Neuron Projection Development Actomyosin Structure Organization Cell Projection Morphogenesis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Regulation Of ATPase Activity Positive Regulation Of Immune System Process Regulation Of Organelle Organization Anatomical Structure Development Fc Receptor Signaling Pathway Cell Activation Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Neuron Development Regulation Of Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Component Biogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Tagcloud ?		alteration alterations arf cadps2 frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional tumors	abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin
Tagcloud (Difference) ?		alteration alterations arf cadps2 frequently gain genomic hot ink4a instability mutants mutation mutations obvious p16 p53 piwil4 point prepared reason restraining resulting saos specificity spot suppresses suppressor transcriptional tumors	abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin
Tagcloud (Intersection) ?