PSAP and CD1B

Number of citations of the paper that reports this interaction (PMID 14716313)
39

Data Source:
HPRD (in vitro)

		PSAP	CD1B
Gene Name		prosaposin	CD1b molecule
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Nucleolus Mitochondrion Lysosomal Membrane Golgi Apparatus Integral Component Of Membrane Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Lysosomal Membrane Plasma Membrane Cell Surface Endosome Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity Lipid Binding	Protein Binding Beta-2-microglobulin Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Platelet Degranulation Sphingolipid Metabolic Process Glycosphingolipid Metabolic Process Lipid Transport Blood Coagulation Regulation Of Lipid Metabolic Process Platelet Activation Positive Regulation Of Catalytic Activity Regulation Of MAPK Cascade Small Molecule Metabolic Process Prostate Gland Growth Epithelial Cell Differentiation Involved In Prostate Gland Development Cellular Response To Organic Substance	Immune Response Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Sphingolipid metabolism Metabolism of lipids and lipoproteins Glycosphingolipid metabolism Class A/1 (Rhodopsin-like receptors) Platelet degranulation Metabolic disorders of biological oxidation enzymes GPCR ligand binding Peptide ligand-binding receptors Response to elevated platelet cytosolic Ca2+ Platelet activation, signaling and aggregation
Drugs		Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases
GWAS
Protein-Protein Interactions		14 interactors: BACE1 BRCA1 CD1B CELSR1 COPS6 CTSD GBA MAFF SGK223 SMAD2 SMAD9 UBE3A USP4 ZBED1	2 interactors: B2M PSAP
Entrez ID		5660	910
HPRD ID		01460	01775
Ensembl ID		ENSG00000197746	ENSG00000158485
Uniprot IDs		P07602	P29016
PDB IDs		1M12 1N69 1SN6 2DOB 2GTG 2QYP 2R0R 2R1Q 2RB3 2Z9A 3BQP 3BQQ 4DDJ	1GZP 1GZQ 1UQS 2H26 3OV6 3T8X
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Ubiquitination Androgen Receptor Signaling Pathway Protein Autoubiquitination Positive Regulation Of Histone H4-K20 Methylation Sperm Entry Positive Regulation Of Histone H4-K16 Acetylation Protein Localization Involved In Establishment Of Planar Polarity Intracellular Steroid Hormone Receptor Signaling Pathway Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Cellular Protein Modification Process Protein Metabolic Process Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Establishment Of Body Hair Planar Orientation Positive Regulation Of Histone H3-K9 Acetylation Lateral Sprouting Involved In Lung Morphogenesis Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis Glucosylceramide Catabolic Process Urogenital System Development Response To Organic Cyclic Compound Cellular Response To Organic Cyclic Compound Organ Growth Cellular Response To Tumor Necrosis Factor Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Zygotic Specification Of Dorsal/ventral Axis Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Protein Modification By Small Protein Removal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Mesonephros Development Response To Tumor Necrosis Factor Glucosylceramide Metabolic Process Cellular Response To Indole-3-methanol Establishment Of Planar Polarity Of Embryonic Epithelium Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Mesoderm Development Negative Regulation Of Centriole Replication Primary MiRNA Processing Sphingosine Biosynthetic Process Embryo Development Kidney Epithelium Development Dosage Compensation By Inactivation Of X Chromosome Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Sphingoid Biosynthetic Process	Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Cell Activation Neuronal Ion Channel Clustering Epithelial Cell Differentiation Involved In Prostate Gland Development Protein Refolding Prostate Gland Growth Regulation Of Defense Response To Virus By Virus Neuron Maturation Respiratory Gaseous Exchange Response To Cadmium Ion Retina Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent T Cell Differentiation In Thymus Prostate Gland Development Platelet Degranulation Glycosphingolipid Metabolic Process Cellular Response To Organic Substance Regulation Of Defense Response To Virus Positive Regulation Of T Cell Mediated Cytotoxicity Regulation Of T Cell Mediated Cytotoxicity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Leukocyte Mediated Cytotoxicity Organ Growth Positive Regulation Of T Cell Mediated Immunity Zymogen Activation Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Iron Ion Homeostasis Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Glycolipid Metabolic Process Response To Organic Substance Positive Regulation Of Peptidase Activity Cellular Response To Interferon-gamma Cell Maturation Transition Metal Ion Homeostasis Positive Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I T Cell Differentiation Sphingolipid Metabolic Process
Tagcloud ?		ac acinar adenocarcinoma cdx2 cea ck20 ck7 dac debated erg gleason hmwck immunomarkers ki lysozyme morphotypes overlap p16 p504s p63 patchy pax prolactin prostatic prostein psma slides villin	arranged cd1a cd1c cd1d cd1e cloning code consist cosmid cosmids distant evenly exception histocompatibility linkage mhc microglobulin orientation overlapping pulse relatives serologically spaced spanned thymocyte tight walking wts
Tagcloud (Difference) ?		ac acinar adenocarcinoma cdx2 cea ck20 ck7 dac debated erg gleason hmwck immunomarkers ki lysozyme morphotypes overlap p16 p504s p63 patchy pax prolactin prostatic prostein psma slides villin	arranged cd1a cd1c cd1d cd1e cloning code consist cosmid cosmids distant evenly exception histocompatibility linkage mhc microglobulin orientation overlapping pulse relatives serologically spaced spanned thymocyte tight walking wts
Tagcloud (Intersection) ?