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PSAP
Gene Name
prosaposin
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleoplasm
Nucleolus
Mitochondrion
Lysosomal Membrane
Golgi Apparatus
Integral Component Of Membrane
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Enzyme Activator Activity
Lipid Binding
Biological Process
Platelet Degranulation
Sphingolipid Metabolic Process
Glycosphingolipid Metabolic Process
Lipid Transport
Blood Coagulation
Regulation Of Lipid Metabolic Process
Platelet Activation
Positive Regulation Of Catalytic Activity
Regulation Of MAPK Cascade
Small Molecule Metabolic Process
Prostate Gland Growth
Epithelial Cell Differentiation Involved In Prostate Gland Development
Cellular Response To Organic Substance
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Sphingolipid metabolism
Metabolism of lipids and lipoproteins
Glycosphingolipid metabolism
Class A/1 (Rhodopsin-like receptors)
Platelet degranulation
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Peptide ligand-binding receptors
Response to elevated platelet cytosolic Ca2+
Platelet activation, signaling and aggregation
Drugs
Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases
GWAS
Protein-protein Interactions
14 interactors:
BACE1
BRCA1
CD1B
CELSR1
COPS6
CTSD
GBA
MAFF
SGK223
SMAD2
SMAD9
UBE3A
USP4
ZBED1
Entrez ID
5660
HPRD ID
01460
Ensembl ID
ENSG00000197746
Uniprot IDs
P07602
PDB IDs
1M12
1N69
1SN6
2DOB
2GTG
2QYP
2R0R
2R1Q
2RB3
2Z9A
3BQP
3BQQ
4DDJ
Enriched GO Terms of Interacting Partners
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Regulation Of Protein Ubiquitination
Androgen Receptor Signaling Pathway
Protein Autoubiquitination
Positive Regulation Of Histone H4-K20 Methylation
Sperm Entry
Positive Regulation Of Histone H4-K16 Acetylation
Protein Localization Involved In Establishment Of Planar Polarity
Intracellular Steroid Hormone Receptor Signaling Pathway
Chordate Embryonic Development
Embryo Development Ending In Birth Or Egg Hatching
Cellular Protein Modification Process
Protein Metabolic Process
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Establishment Of Body Hair Planar Orientation
Positive Regulation Of Histone H3-K9 Acetylation
Lateral Sprouting Involved In Lung Morphogenesis
Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Glucosylceramide Catabolic Process
Urogenital System Development
Response To Organic Cyclic Compound
Cellular Response To Organic Cyclic Compound
Organ Growth
Cellular Response To Tumor Necrosis Factor
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Zygotic Specification Of Dorsal/ventral Axis
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Protein Modification By Small Protein Removal
Dichotomous Subdivision Of Terminal Units Involved In Lung Branching
Mesonephros Development
Response To Tumor Necrosis Factor
Glucosylceramide Metabolic Process
Cellular Response To Indole-3-methanol
Establishment Of Planar Polarity Of Embryonic Epithelium
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Mesoderm Development
Negative Regulation Of Centriole Replication
Primary MiRNA Processing
Sphingosine Biosynthetic Process
Embryo Development
Kidney Epithelium Development
Dosage Compensation By Inactivation Of X Chromosome
Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Regulation Of Nodal Signaling Pathway
Common-partner SMAD Protein Phosphorylation
Sphingoid Biosynthetic Process
Tagcloud
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ac
acinar
adenocarcinoma
cdx2
cea
ck20
ck7
dac
debated
erg
gleason
hmwck
immunomarkers
ki
lysozyme
morphotypes
overlap
p16
p504s
p63
patchy
pax
prolactin
prostatic
prostein
psma
slides
villin