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UBA6 and UBE2T
Number of citations of the paper that reports this interaction (PubMedID
37604583
)
54
Data Source:
BioGRID
(enzymatic study)
UBA6
UBE2T
Description
ubiquitin like modifier activating enzyme 6
ubiquitin conjugating enzyme E2 T
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Nucleus
Nucleoplasm
Nucleolus
Molecular Function
Nucleotide Binding
Ubiquitin Activating Enzyme Activity
Protein Binding
ATP Binding
Ubiquitin-like Modifier Activating Enzyme Activity
Ligase Activity
FAT10 Activating Enzyme Activity
Metal Ion Binding
Nucleotide Binding
Chromatin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Ubiquitin-dependent Protein Catabolic Process
DNA Damage Response
Protein Ubiquitination
Protein Polyubiquitination
DNA Repair
Protein Monoubiquitination
DNA Damage Response
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein K29-linked Ubiquitination
Protein K27-linked Ubiquitination
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Fanconi Anemia Pathway
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS
Regular attendance at a pub or social club (
29970889
)
Breast cancer (
23535733
)
Celiac disease (
23936387
)
Interacting Genes
26 interacting genes:
BIRC6
HMBOX1
HUWE1
JUNB
LMO2
OTUB1
SMAD9
UBC
UBD
UBE2A
UBE2B
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2G2
UBE2L3
UBE2L6
UBE2O
UBE2S
UBE2T
UBE2Z
25 interacting genes:
AMFR
ARIH2
BRCA1
CDK2
CHEK1
FANCD2
FANCL
LNX2
MARCHF5
MGRN1
PCGF2
PRKCG
PRKN
RNF128
RNF144B
RNF167
RNF31
RNF4
ROCK1
RPS6KA1
TRIM27
UBA1
UBA6
UBC
ZNRF2
Entrez ID
55236
29089
HPRD ID
13341
13704
Ensembl ID
ENSG00000033178
ENSG00000077152
Uniprot IDs
A0AVT1
Q9NPD8
PDB IDs
7PVN
7PYV
7SOL
1YH2
4CCG
5NGZ
5OJJ
6R75
7KZR
7KZS
7KZT
7KZV
8JUC
8JVD
8JVE
8JVL
Enriched GO Terms of Interacting Partners
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Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Protein Ubiquitination
Post-translational Protein Modification
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Modification-dependent Protein Catabolic Process
Protein Modification Process
Proteolysis Involved In Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-like Protein Transferase Activity
Macromolecule Catabolic Process
Proteolysis
Transferase Activity
Protein Metabolic Process
Protein Monoubiquitination
ATP Binding
Protein K63-linked Ubiquitination
Nucleoplasm
Catabolic Process
Nucleotide Binding
Macromolecule Metabolic Process
ISG15 Transferase Activity
Proteasomal Protein Catabolic Process
Protein K6-linked Ubiquitination
ISG15-protein Conjugation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Nucleus
Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Protein K29-linked Ubiquitination
Ubiquitin Protein Ligase Activity
Regulation Of Post-translational Protein Modification
Positive Regulation Of Post-translational Protein Modification
Protein K27-linked Ubiquitination
Cytosol
Protein Autoubiquitination
Ubiquitin Protein Ligase Binding
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Targeting To Mitochondrion
HULC Complex
Positive Regulation Of Establishment Of Protein Localization To Mitochondrion
Positive Regulation Of Ubiquitin Protein Ligase Activity
Regulation Of Protein Targeting To Mitochondrion
Free Ubiquitin Chain Polymerization
DNA Metabolic Process
DNA Repair
Cell Cycle Phase Transition
Protein Ubiquitination
Post-translational Protein Modification
Protein Modification By Small Protein Conjugation
Protein Modification Process
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Transferase Activity
Protein Polyubiquitination
Protein Metabolic Process
Zinc Ion Binding
Metal Ion Binding
Modification-dependent Protein Catabolic Process
Macromolecule Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Protein K63-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Ubiquitin Ligase Complex
Protein Autoubiquitination
Protein K6-linked Ubiquitination
Macromolecule Catabolic Process
Proteolysis
Response To Stress
Cellular Response To Stress
Protein K27-linked Ubiquitination
Mitotic DNA Damage Checkpoint Signaling
Mitotic DNA Integrity Checkpoint Signaling
Cytosol
Ubiquitin Activating Enzyme Activity
DNA Damage Response
DNA Damage Checkpoint Signaling
Ubiquitin Conjugating Enzyme Binding
Condensed Chromosome
Negative Regulation Of Programmed Cell Death
Regulation Of Organelle Organization
Catabolic Process
Regulation Of Protein Targeting To Mitochondrion
Ubiquitin Protein Ligase Binding
Signal Transduction In Response To DNA Damage
Protein Monoubiquitination
Cytoplasm
Ubiquitin-like Modifier Activating Enzyme Activity
Negative Regulation Of Signal Transduction
Intracellular Signal Transduction
Positive Regulation Of Autophagy
Negative Regulation Of Cell Cycle
Protein Serine Kinase Activity
Protein K29-linked Ubiquitination
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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