UBA6 and UBE2G2

Number of citations of the paper that reports this interaction (PMID 17597759)
66

Data Source:
BioGRID (pull down)

		UBA6	UBE2G2
Gene Name		ubiquitin-like modifier activating enzyme 6	ubiquitin-conjugating enzyme E2G 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol	Endoplasmic Reticulum Cytosol
	Molecular Function	Protein Binding ATP Binding FAT10 Activating Enzyme Activity	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination	Ubiquitin-dependent Protein Catabolic Process Protein N-linked Glycosylation Via Asparagine ER-associated Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: HMBOX1 SMAD9 UBD UBE2D1 UBE2D2 UBE2D3 UBE2G2 UBE2L3 UBE2L6 UBE2S UBE2T UBE2Z	37 interactors: AMFR ARL14 BIRC8 CBL CNNM3 CPOX CUL9 FARP2 HBS1L HERPUD1 KDM2A KIAA0368 MDM2 MGRN1 MLLT6 MUL1 NDUFS4 PARK2 POLR3F RBX1 RFFL RNF111 RNF146 RNF157 RNF168 RNF26 RNF5 TMEM45B TRIM3 TRIM43 UBA1 UBA6 UBC UBE2J2 UBE3A VAMP8 ZNRF4
Entrez ID		55236	7327
HPRD ID		13341	04387
Ensembl ID			ENSG00000184787
Uniprot IDs		A0AVT1	P60604
PDB IDs			2CYX 2KLY 2LXP 3H8K 4LAD
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Proteolysis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Catabolic Process Protein Metabolic Process Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Protein K6-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Proteasomal Protein Catabolic Process Positive Regulation Of Ligase Activity BMP Signaling Pathway Toll-like Receptor 4 Signaling Pathway Response To Hypoxia Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Cellular Metabolic Process Activation Of Innate Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Innate Immune Response Response To Transforming Growth Factor Beta Protein K63-linked Ubiquitination Regulation Of Protein Ubiquitination Protein Monoubiquitination	Protein Ubiquitination Protein Modification By Small Protein Conjugation Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Polyubiquitination Catabolic Process Proteolysis Cellular Protein Metabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K48-linked Ubiquitination Protein Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Cellular Response To Stress Cellular Metabolic Process Regulation Of Proteolysis Regulation Of Signaling Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Signal Transduction Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Protein Ubiquitination Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Signal Transduction Protein K63-linked Ubiquitination Cellular Response To Topologically Incorrect Protein Negative Regulation Of Mitochondrial Fusion Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Signaling Regulation Of Mitochondrial Fusion Protein Autoubiquitination Response To Stimulus Response To Unfolded Protein Regulation Of Protein Stability Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Catabolic Process Cellular Response To Stimulus Response To Organic Substance Positive Regulation Of Mitochondrial Fission Regulation Of Intracellular Signal Transduction Response To Stress Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		adopted annotation artificial bands buffalo concise dodecyl enolase ensure estrous estrus immunoblot indicator insemination lactoperoxidase noninvasive page phases polyacrylamide precisely proteome proteomic saliva sds serotransferrin tgm3 tlr toll transducin	alters assembly attack bond catalyzes chain chains cooperative cooperatively correct cue distal donor drive e3 elusive g2br gp78 helps lys48 monoubiquitin orientation polyubiquitin preassembled preferential thioester transferring ubiquitin
Tagcloud (Difference) ?		adopted annotation artificial bands buffalo concise dodecyl enolase ensure estrous estrus immunoblot indicator insemination lactoperoxidase noninvasive page phases polyacrylamide precisely proteome proteomic saliva sds serotransferrin tgm3 tlr toll transducin	alters assembly attack bond catalyzes chain chains cooperative cooperatively correct cue distal donor drive e3 elusive g2br gp78 helps lys48 monoubiquitin orientation polyubiquitin preassembled preferential thioester transferring ubiquitin
Tagcloud (Intersection) ?