SGTA and TWSG1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SGTA	TWSG1
Gene Name		small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	twisted gastrulation BMP signaling modulator 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Protein Binding
	Biological Process	Biological_process Viral Process	Ossification Mesoderm Formation Salivary Gland Morphogenesis Hemopoiesis Cell Differentiation BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS			Dental caries ( 23064961)
Protein-Protein Interactions		92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B	4 interactors: BMP1 BMP4 CHRD SGTA
Entrez ID		6449	57045
HPRD ID		04568	05443
Ensembl ID		ENSG00000104969	ENSG00000128791
Uniprot IDs		O43765	Q9GZX9
PDB IDs		2VYI 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?		Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process	Ossification Positive Regulation Of Cartilage Development Regulation Of Mesenchymal Cell Proliferation Skeletal System Development BMP Signaling Pathway Regulation Of BMP Signaling Pathway Mesoderm Formation Regulation Of Cartilage Development Mesoderm Morphogenesis Regulation Of Stem Cell Proliferation Dorsal/ventral Pattern Formation Negative Regulation Of Metanephric S-shaped Body Morphogenesis Negative Regulation Of Metanephric Comma-shaped Body Morphogenesis BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Mesenchymal Cell Proliferation Involved In Ureter Development Ureter Epithelial Cell Differentiation Negative Regulation Of Mesenchymal Cell Proliferation Involved In Ureter Development Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Pulmonary Artery Endothelial Tube Morphogenesis BMP Signaling Pathway Involved In Renal System Segmentation BMP Signaling Pathway Involved In Ureter Morphogenesis Negative Regulation Of Branch Elongation Involved In Ureteric Bud Branching By BMP Signaling Pathway Specification Of Ureteric Bud Anterior/posterior Symmetry By BMP Signaling Pathway Positive Regulation Of Cardiac Muscle Fiber Development Bud Dilation Involved In Lung Branching Epithelial Cell Proliferation Involved In Lung Morphogenesis BMP Signaling Pathway Involved In Nephric Duct Formation Intermediate Mesodermal Cell Differentiation Regulation Of Osteoblast Differentiation Formation Of Primary Germ Layer Osteoblast Differentiation Mesoderm Development Intermediate Mesoderm Development Gastrulation Neural Tube Development Cartilage Development Regulation Of Ossification Negative Regulation Of Glomerular Mesangial Cell Proliferation Ureter Urothelium Development Mesenchymal Cell Proliferation Involved In Ureteric Bud Development Cloacal Septation Negative Regulation Of Glomerulus Development Mesodermal Cell Fate Determination BMP Signaling Pathway Involved In Heart Induction Deltoid Tuberosity Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Connective Tissue Development Ureter Morphogenesis Ureter Smooth Muscle Cell Differentiation Regulation Of Branch Elongation Involved In Ureteric Bud Branching
Tagcloud ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	acted anomaly bmp bmp2 concert dams e11 e9 embryonal expressivity forebrain gastrulation gavage geometric holoprosencephaly hpe manifested microct midface midline morphometric narrowing ntd overt p19 penetrance predisposing teratogenesis twisted
Tagcloud (Difference) ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	acted anomaly bmp bmp2 concert dams e11 e9 embryonal expressivity forebrain gastrulation gavage geometric holoprosencephaly hpe manifested microct midface midline morphometric narrowing ntd overt p19 penetrance predisposing teratogenesis twisted
Tagcloud (Intersection) ?