Wiki-Pi
About
Search
People
Updates
Search
SGTA and CDSN
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
SGTA
CDSN
Description
small glutamine rich tetratricopeptide repeat co-chaperone alpha
corneodesmosin
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
TRC Complex
Cornified Envelope
Extracellular Region
Plasma Membrane
Cell-cell Junction
Desmosome
Molecular Function
Protein Binding
Identical Protein Binding
Molecular Adaptor Activity
BAT3 Complex Binding
Protein Homodimerization Activity
Biological Process
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
ERAD Pathway
Tail-anchored Membrane Protein Insertion Into ER Membrane
Negative Regulation Of ERAD Pathway
Positive Regulation Of ERAD Pathway
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Corneocyte Desquamation
Cell Adhesion
Epidermis Development
Keratinocyte Differentiation
Skin Morphogenesis
Cell-cell Adhesion
Negative Regulation Of Cornification
Amyloid Fibril Formation
Pathways
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Formation of the cornified envelope
Drugs
Diseases
Hypotrichosis simplex of scalp
GWAS
Femur bone mineral density x serum urate levels interaction (
34046847
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Automobile speeding propensity (
30643258
)
Hematology traits (
23263863
)
Hemoglobin levels (
32327693
)
Hip circumference adjusted for BMI (
34021172
)
HIV-1 control (
20041166
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Multiple myeloma (
23955597
)
Schizophrenia (
28991256
)
Systemic mastocytosis (
32752121
)
Takayasu arteritis (
25604533
)
Ulcerative colitis (
28067908
)
White blood cell count (
21738480
20139978
)
Interacting Genes
182 interacting genes:
ADAM21
ADIPOQ
ADRM1
AGR2
AGR3
AOC3
BAG6
BCL2L12
BTC
C1QA
C1QL4
C1QTNF1
C1QTNF5
C1QTNF6
C3orf52
C5orf46
CD79B
CD99
CD99L2
CDH15
CDSN
CHRNG
COL1A2
COL8A2
CREB3L3
CSF1
CST1
CTAG1A
CTAG1B
CTSL
CXCL8
CYB5R1
DEFA6
DEFB131A
DKK3
DMKN
EDA2R
EDAR
EFEMP1
EFEMP2
ERP27
ERP29
ETNK1
EVA1B
F11R
FERD3L
FGF21
FIP1L1
FKBP7
FSTL1
FXYD2
FXYD7
FZD7
GABARAPL2
GAL
GALP
GHR
GIP
GPX7
GRN
GUCA2A
GYPA
HSP90AA1
HSP90AB1
HSPA13
HSPA4
IER3
IGFBP6
IGL
IGLC1
IL6ST
IRF3
IRF5
ITPRIPL1
KASH5
KCNA1
KCNA10
KCNE5
KLHL20
KRT6A
KTN1
LAIR2
LAT
LCN2
LDLRAD4
LSMEM2
MRAP2
MS4A3
MSMB
MSTN
MYDGF
MYOC
NAXD
NME3
NPVF
NR3C1
NRSN2
NXF1
PAGE3
PBXIP1
PCDHA4
PCDHGA4
PFN2
PGLYRP2
PGR
PIAS1
PLAAT4
PMEPA1
PODXL
PPIB
PPIC
PPP1R3C
PRAP1
PRB4
PRRG2
PSORS1C2
PTN
PYY
RCN1
RNASE10
RNF144A
RNF144B
RNF170
RPN1
SDC4
SDF2L1
SERPINE1
SERPINI2
SGCA
SGTB
SHISA4
SHISA5
SLPI
SMAGP
SMIM14
SMIM5
SOD3
SPINK9
SPN
SPP1
SPPL2A
SRGN
SRL
STMP1
SUOX
SYT11
SYT4
TFF3
TFRC
TGFA
TIAM1
TMEM154
TMEM174
TMEM230
TMEM31
TMEM98
TMPO
TMPRSS11D
TMUB2
TNFRSF10C
TNFRSF13B
TNFRSF19
TNFRSF1A
TNFRSF21
TNFSF12
TRIM5
TWSG1
TXNDC12
UBL4A
UBQLN2
UPK3A
USP14
USP5
USP9X
VIP
WBP1L
WFDC12
WFDC13
WFDC5
ZBTB8B
ZG16
ZG16B
37 interacting genes:
ASPH
ATXN1L
BAG6
BANP
CCHCR1
CEP55
CSTF2
CSTF2T
CTNNA3
DESI1
EIF3F
ENKD1
EXOC8
FAM9B
HGS
HPCAL4
ITPRIPL1
KCNIP3
KLK7
LCN2
NCS1
NELFCD
PARVG
PLVAP
PRKAB2
SGTA
SGTB
SMARCD1
TGM7
TRIM69
TSGA10
UBQLN1
UBQLN2
UBQLN4
UCHL5
VSNL1
ZDHHC17
Entrez ID
6449
1041
HPRD ID
04568
03998
Ensembl ID
ENSG00000104969
ENSG00000204539
Uniprot IDs
O43765
Q15517
PDB IDs
2VYI
4CPG
4GOD
4GOE
4GOF
Enriched GO Terms of Interacting Partners
?
Extracellular Region
Extracellular Space
Protein Binding
Endoplasmic Reticulum Lumen
Response To Bacterium
Defense Response To Bacterium
Collagen Trimer
Response To Stress
Membrane
Response To Other Organism
Antimicrobial Humoral Response
Endoplasmic Reticulum
Immune System Process
Regulation Of Immune System Process
Humoral Immune Response
Peptidase Inhibitor Activity
Negative Regulation Of Cell Activation
Positive Regulation Of Leukocyte Migration
Serine-type Endopeptidase Inhibitor Activity
Defense Response
Extracellular Exosome
Defense Response To Symbiont
Negative Regulation Of Proteasomal Protein Catabolic Process
Antibacterial Humoral Response
Plasma Membrane
Immune Response
Defense Response To Other Organism
Negative Regulation Of Leukocyte Activation
Identical Protein Binding
Negative Regulation Of Cell Adhesion
Positive Regulation Of MAPK Cascade
Response To External Biotic Stimulus
Tumor Necrosis Factor Receptor Activity
Negative Regulation Of Proteolysis
Positive Regulation Of Intracellular Signal Transduction
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Positive Regulation Of Immune System Process
Hormone Activity
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Glucocorticoid Metabolic Process
Growth Factor Activity
Fibronectin Binding
Macrophage Apoptotic Process
BAT3 Complex
Regulation Of Cell Adhesion
Protein Folding
Negative Regulation Of Cell-cell Adhesion
Negative Regulation Of Lymphocyte Proliferation
Epidermal Growth Factor Receptor Binding
Negative Regulation Of Mononuclear Cell Proliferation
Positive Regulation Of ERAD Pathway
Regulation Of ERAD Pathway
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Proteolysis
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Regulation Of Protein Catabolic Process
Polyubiquitin Modification-dependent Protein Binding
Identical Protein Binding
TRC Complex
Protein Targeting To ER
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Response To Endoplasmic Reticulum Stress
Establishment Of Protein Localization To Endoplasmic Reticulum
ERAD Pathway
Positive Regulation Of Proteolysis
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Cellular Response To Stress
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
Centriole
Protein Targeting To Membrane
Tail-anchored Membrane Protein Insertion Into ER Membrane
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Molecular Adaptor Activity
Negative Regulation Of Proteolysis Involved In Protein Catabolic Process
Proteasome Binding
Autophagosome
Proteolysis
Regulation Of Macroautophagy
Localization Within Membrane
Protein Targeting
Protein Binding
Positive Regulation Of Protein Catabolic Process
Regulation Of Protein Metabolic Process
Establishment Of Protein Localization
Cytoplasm
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?