SGTA and SLPI

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SGTA	SLPI
Gene Name		small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	secretory leukocyte peptidase inhibitor
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding
	Biological Process	Biological_process Viral Process	Negative Regulation Of Endopeptidase Activity Negative Regulation Of Protein Binding Negative Regulation Of Viral Genome Replication
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B	10 interactors: CTSB CTSL CTSS ELANE FAM9B GRN KLK3 PLSCR1 PRSS2 SGTA
Entrez ID		6449	6590
HPRD ID		04568	00121
Ensembl ID		ENSG00000104969	ENSG00000124107
Uniprot IDs		O43765	P03973
PDB IDs		2VYI 4GOD 4GOE 4GOF	2Z7F 4DOQ
Enriched GO Terms of Interacting Partners?		Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process	Extracellular Matrix Disassembly Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Response To Thyroid Hormone Stimulus Response To Thyroid Hormone Defense Response Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Immune Response Acute Inflammatory Response Proteolysis Regulation Of Immune Response Toll-like Receptor Signaling Pathway Positive Regulation Of Immune System Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Immune System Process Response To Stress Immune Response Protein Catabolic Process Regulation Of Immune System Process Regulation Of Inflammatory Response Innate Immune Response Catabolic Process Inflammatory Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response-regulating Signaling Pathway Positive Regulation Of Inflammatory Response Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Factor XII Activation Neutrophil Mediated Killing Of Fungus Basement Membrane Disassembly Macrophage Apoptotic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Response To Organic Substance Response To Stimulus Positive Regulation Of Fibrinolysis Negative Regulation Of Chemokine Biosynthetic Process Negative Regulation Of Interleukin-8 Biosynthetic Process Response To Yeast Phosphatidylserine Biosynthetic Process
Tagcloud ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	21x 72x a2 a2t annexin attributed correlating embedded entities facilitating formalin heterotetramer hnscc hnsccs hpv inverse lab nonsmokers paraffin protect protects putatively scc separately smokers supports surplus tobacco tonsillar
Tagcloud (Difference) ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	21x 72x a2 a2t annexin attributed correlating embedded entities facilitating formalin heterotetramer hnscc hnsccs hpv inverse lab nonsmokers paraffin protect protects putatively scc separately smokers supports surplus tobacco tonsillar
Tagcloud (Intersection) ?