SGTA and MSTN

Number of citations of the paper that reports this interaction (PMID 14623262)
3

Data Source:
HPRD (in vitro, in vivo)

		SGTA	MSTN
Gene Name		small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	myostatin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Extracellular Space Cytoplasm
	Molecular Function	Protein Binding	Receptor Binding Cytokine Activity Transforming Growth Factor Beta Receptor Binding Protein Binding Growth Factor Activity Heparin Binding Identical Protein Binding
	Biological Process	Biological_process Viral Process	Transforming Growth Factor Beta Receptor Signaling Pathway Muscle Organ Development Response To Heat Response To Gravity Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Skeletal Muscle Atrophy Negative Regulation Of Muscle Hypertrophy Response To Muscle Activity Ovulation Cycle Process Response To Testosterone Regulation Of Apoptotic Process Skeletal Muscle Tissue Regeneration Regulation Of MAPK Cascade Response To Estrogen Response To Ethanol Positive Regulation Of Transcription, DNA-templated Cell Development Negative Regulation Of Skeletal Muscle Tissue Growth Response To Electrical Stimulus SMAD Protein Signal Transduction Cellular Response To Dexamethasone Stimulus Negative Regulation Of Skeletal Muscle Satellite Cell Proliferation Negative Regulation Of Satellite Cell Differentiation Negative Regulation Of Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B	6 interactors: ACVR2B APP FSTL3 SGTA TCAP WFIKKN2
Entrez ID		6449	2660
HPRD ID		04568	03474
Ensembl ID		ENSG00000104969	ENSG00000138379
Uniprot IDs		O43765	O14793 Q53S46
PDB IDs		2VYI 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?		Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process	Regulation Of Activin Receptor Signaling Pathway Muscle Fiber Development Palate Development Cell Differentiation Synaptic Growth At Neuromuscular Junction Regulation Of Protein Binding Striated Muscle Cell Development Sarcomerogenesis Collateral Sprouting In Absence Of Injury Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Muscle Cell Development System Development Collateral Sprouting Axon Midline Choice Point Recognition Myosin Filament Assembly Striated Muscle Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Multicellular Organismal Development Axon Choice Point Recognition Skeletal Muscle Thin Filament Assembly Lung Development Anterior/posterior Pattern Specification Respiratory Tube Development Regulation Of Binding Negative Regulation Of Endopeptidase Activity Positive Regulation Of Activin Receptor Signaling Pathway Anatomical Structure Development Negative Regulation Of Peptidase Activity Cardiac Muscle Fiber Development Response To Muscle Stretch Skeletal Myofibril Assembly Lymphatic Endothelial Cell Differentiation Respiratory System Development Neuron Remodeling Negative Regulation Of Activin Receptor Signaling Pathway Kidney Development Muscle Cell Differentiation Otic Vesicle Formation Renal System Development Lymphangiogenesis Organ Development Negative Regulation Of Proteolysis Otic Vesicle Morphogenesis Developmental Process Lymph Vessel Morphogenesis Negative Regulation Of Protein Processing Urogenital System Development Regulation Of Endopeptidase Activity
Tagcloud ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	adenoviral adenovirus aforesaid backgrounds conversion decades ectopic electroporation eliminating facilitated fibroblasts fos lentiviral master muscle muscles myoblasts myod myogenesis myogenic myostatin myotubes negligible offers scarcity take transduced transducing wasting
Tagcloud (Difference) ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	adenoviral adenovirus aforesaid backgrounds conversion decades ectopic electroporation eliminating facilitated fibroblasts fos lentiviral master muscle muscles myoblasts myod myogenesis myogenic myostatin myotubes negligible offers scarcity take transduced transducing wasting
Tagcloud (Intersection) ?