SGTA and F11R

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SGTA	F11R
Gene Name		small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	F11 receptor
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Plasma Membrane Cell-cell Junction Tight Junction Microtubule Cytoskeleton Integral Component Of Membrane Cell Junction Cytoplasmic Vesicle Slit Diaphragm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding PDZ Domain Binding
	Biological Process	Biological_process Viral Process	Inflammatory Response Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Blood Coagulation Response To Radiation Viral Process Extracellular Matrix Organization Actomyosin Structure Organization Positive Regulation Of Rap GTPase Activity Negative Regulation Of Rho GTPase Activity Cell Junction Assembly Cell-cell Junction Organization Positive Regulation Of Blood Pressure Intestinal Absorption Leukocyte Migration Tight Junction Assembly Establishment Of Protein Localization To Plasma Membrane Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Regulation Of Actin Cytoskeleton Reorganization
Pathways			Loss of Function of TGFBR2 in Cancer Cell junction organization TGFBR2 MSI Frameshift Mutants in Cancer TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) SMAD2/3 Phosphorylation Motif Mutants in Cancer Tight junction interactions Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer TGFBR1 KD Mutants in Cancer TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Cell surface interactions at the vascular wall Cell-cell junction organization Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer Integrin cell surface interactions SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B	16 interactors: ASIP BDNF CASK CGN CSNK2A1 F2RL2 ITGAL MLLT4 MPDZ PARD3 PEX19 PICK1 PRKCA PTPRB SGTA TJP1
Entrez ID		6449	50848
HPRD ID		04568	12038
Ensembl ID		ENSG00000104969	ENSG00000158769
Uniprot IDs		O43765	B7Z941 Q6FIB4 Q9Y624
PDB IDs		2VYI 4GOD 4GOE 4GOF	1NBQ 3EOY 3TSZ
Enriched GO Terms of Interacting Partners?		Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process	Cell Junction Assembly Cell-cell Junction Organization Cell-cell Junction Assembly Establishment Of Endothelial Intestinal Barrier Signal Transduction Epithelial Cell Development Membrane Organization Cell-cell Signaling Signaling Cell Communication Anatomical Structure Development Protein Localization To Membrane Cell Development Cellular Response To Stimulus Developmental Process Establishment Of Endothelial Barrier Epithelial Cell Differentiation Cell Surface Receptor Signaling Pathway Endothelial Cell Development Tight Junction Assembly Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Epithelial Cell Morphogenesis Epithelium Development Anatomical Structure Morphogenesis Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Wound Healing Response To Growth Factor Receptor Clustering Tissue Development G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Involved In Cell-cell Junction Organization Response To Anesthetic Negative Regulation Of Lipid Binding Positive Regulation Of Dense Core Granule Biogenesis Response To Fluoxetine Response To L-glutamate Cell Differentiation Cell Adhesion Chaperone-mediated Protein Folding Negative Regulation Of Synaptic Transmission Cellular Response To Organic Substance Response To Wounding Response To Stimulus Locomotion Apical Junction Assembly Cell Morphogenesis Involved In Differentiation Endothelial Cell Differentiation Cellular Response To Carbohydrate Stimulus Multicellular Organismal Development
Tagcloud ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Difference) ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Intersection) ?