SGTA and GIP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SGTA	GIP
Gene Name		small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	gastric inhibitory polypeptide
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule Lumen Neuronal Cell Body
	Molecular Function	Protein Binding	Hormone Activity
	Biological Process	Biological_process Viral Process	Signal Transduction Female Pregnancy Memory Adult Locomotory Behavior Response To Glucose Response To Selenium Ion Positive Regulation Of Glucose Transport Response To Organic Cyclic Compound Sensory Perception Of Pain Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Response To Lipid Exploration Behavior Response To Drug Response To Starvation Response To Amino Acid Response To Peptide Hormone Positive Regulation Of CAMP-mediated Signaling Cellular Protein Metabolic Process Response To Axon Injury Regulation Of Insulin Secretion Digestive System Development Long-term Synaptic Potentiation Positive Regulation Of Glucagon Secretion Triglyceride Homeostasis
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR G alpha (s) signalling events Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Glucagon-type ligand receptors GPCR ligand binding Metabolic disorders of biological oxidation enzymes Peptide hormone metabolism GPCR downstream signaling Class B/2 (Secretin family receptors) Incretin synthesis, secretion, and inactivation
Drugs
Diseases
GWAS			Coronary heart disease ( 21378990)
Protein-Protein Interactions		92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B	5 interactors: ADAMTSL4 GIPR KRTAP10-3 NOTCH2NL SGTA
Entrez ID		6449	2695
HPRD ID		04568	15925
Ensembl ID		ENSG00000104969	ENSG00000159224
Uniprot IDs		O43765	P09681
PDB IDs		2VYI 4GOD 4GOE 4GOF	1T5Q 2B4N 2L70 2L71 2OBU 2QKH
Enriched GO Terms of Interacting Partners?		Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process	Gastric Inhibitory Peptide Signaling Pathway
Tagcloud ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	32pua aspirated aspiration corp curved cystadenomas cytologic eum eus fg gauge grassau medizin melville negatives ny olympus orangeburg passes pentax pseudocyst resolving rtfna rtfnas staging suspicious technik tomographic unsuccessful
Tagcloud (Difference) ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	32pua aspirated aspiration corp curved cystadenomas cytologic eum eus fg gauge grassau medizin melville negatives ny olympus orangeburg passes pentax pseudocyst resolving rtfna rtfnas staging suspicious technik tomographic unsuccessful
Tagcloud (Intersection) ?