SGTA and BCL2L12

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SGTA	BCL2L12
Gene Name		small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	BCL2-like 12 (proline rich)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Membrane
	Molecular Function	Protein Binding	P53 Binding Protein Binding
	Biological Process	Biological_process Viral Process	Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cellular Senescence
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B	2 interactors: BCL2L1 SGTA
Entrez ID		6449	83596
HPRD ID		04568	16543
Ensembl ID		ENSG00000104969
Uniprot IDs		O43765	I6LJZ5 I6LJZ6 I6LJZ7 I6LJZ8 Q9HB09
PDB IDs		2VYI 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?		Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process	Apoptotic Process In Bone Marrow Suppression By Virus Of Host Apoptotic Process Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Viral Process Negative Regulation Of Execution Phase Of Apoptosis Cellular Response To Virus Modulation By Virus Of Host Process Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Anoikis Cellular Response To Gamma Radiation Hepatocyte Apoptotic Process Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Anoikis Negative Regulation Of Protein Localization To Plasma Membrane Modulation By Virus Of Host Morphology Or Physiology Mitochondrion Morphogenesis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Execution Phase Of Apoptosis Release Of Cytochrome C From Mitochondria Negative Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Permeability Cellular Response To Alkaloid Regulation Of Membrane Permeability Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization To Plasma Membrane Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Regulation Of Protein Localization To Plasma Membrane Neuron Apoptotic Process Cellular Response To Ionizing Radiation Cellular Response To Amino Acid Stimulus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Neuron Death Ovarian Follicle Development Apoptotic Mitochondrial Changes Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ovulation Cycle Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Interaction With Host Extrinsic Apoptotic Signaling Pathway Cytokinesis Regulation Of Autophagy Female Gonad Development
Tagcloud ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	anophthalmia asxl1 bohring constitutional cytopenia dwarfism dysplastic favoring granulocytic h3k4me3 haploinsufficient hsc hscs implying kit lethality lin lineage lived malformations malignancies neoplasm opitz recapitulates repopulating skewed surviving
Tagcloud (Difference) ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	anophthalmia asxl1 bohring constitutional cytopenia dwarfism dysplastic favoring granulocytic h3k4me3 haploinsufficient hsc hscs implying kit lethality lin lineage lived malformations malignancies neoplasm opitz recapitulates repopulating skewed surviving
Tagcloud (Intersection) ?