SGTA and GAL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SGTA	GAL
Gene Name		small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	galanin/GMAP prepropeptide
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Extracellular Region Extracellular Space Golgi Apparatus Secretory Granule Neuronal Cell Body
	Molecular Function	Protein Binding	Neuropeptide Hormone Activity Protein Binding Type 1 Galanin Receptor Binding Type 2 Galanin Receptor Binding Type 3 Galanin Receptor Binding
	Biological Process	Biological_process Viral Process	Inflammatory Response Neuropeptide Signaling Pathway Nervous System Development Feeding Behavior Protein Kinase A Signaling CAMP-mediated Signaling Insulin Secretion Regulation Of Glucocorticoid Metabolic Process Response To Insulin Response To Immobilization Stress Response To Drug Positive Regulation Of Apoptotic Process Response To Estrogen Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Cortisol Secretion Positive Regulation Of Catagen Positive Regulation Of Large Conductance Calcium-activated Potassium Channel Activity Negative Regulation Of Root Hair Elongation
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B	4 interactors: GALR1 GALR2 GPR151 SGTA
Entrez ID		6449	51083
HPRD ID		04568	00658
Ensembl ID		ENSG00000104969	ENSG00000069482
Uniprot IDs		O43765	P22466
PDB IDs		2VYI 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?		Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process	Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Negative Regulation Of CAMP Biosynthetic Process Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Regulation Of Adenylate Cyclase Activity Regulation Of Cyclase Activity Regulation Of CAMP Biosynthetic Process Neuropeptide Signaling Pathway Regulation Of CAMP Metabolic Process Digestion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Large Conductance Calcium-activated Potassium Channel Activity Cytosolic Calcium Ion Homeostasis G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cortisol Secretion Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Chemical Homeostasis Ion Homeostasis Synaptic Transmission Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Cellular Homeostasis Positive Regulation Of Transport Positive Regulation Of Cation Channel Activity Negative Regulation Of Catalytic Activity Regulation Of Potassium Ion Transmembrane Transport Chemical Homeostasis Cell Surface Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Ion Transmembrane Transporter Activity Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Transporter Activity Positive Regulation Of Lipid Transport Regulation Of Potassium Ion Transport Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Regulation Of Lipid Transport Feeding Behavior Positive Regulation Of Transcription, DNA-templated
Tagcloud ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	asialoglycoprotein asialoorosomucoid chromatographed competed crosslinked crosslinking crossreacted deglycosylated dithiobis dtssp egta exoglycosidases ghosts glycosidase hepatocytes lactose leu121 lf lfs lys126 lys220 neunac p45 phe198 rhl stripped sulfosuccimidylproprionate triton vigorously
Tagcloud (Difference) ?		bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	asialoglycoprotein asialoorosomucoid chromatographed competed crosslinked crosslinking crossreacted deglycosylated dithiobis dtssp egta exoglycosidases ghosts glycosidase hepatocytes lactose leu121 lf lfs lys126 lys220 neunac p45 phe198 rhl stripped sulfosuccimidylproprionate triton vigorously
Tagcloud (Intersection) ?