SF3B1 and SMAD9

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		SF3B1	SMAD9
Gene Name		splicing factor 3b, subunit 1, 155kDa	SMAD family member 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nuclear Speck Catalytic Step 2 Spliceosome	Intracellular Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol
	Molecular Function	Chromatin Binding Protein Binding Poly(A) RNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity Metal Ion Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Anterior/posterior Pattern Specification Gene Expression	Ureteric Bud Development Response To Hypoxia Mullerian Duct Regression Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway Midbrain Development Hindbrain Development Intracellular Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Cartilage Development Bone Development Cellular Response To Organic Cyclic Compound
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway	Signaling by BMP
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: APBB1 C11orf58 CALM1 CSNK2A1 DYRK1A ERG IL7R MELK MYC NUDT21 PLRG1 PPP1R8 PRPF40A RBM17 SF3B3 SF3B6 SMAD1 SMAD5 SMAD9 SNIP1 TCERG1 TOP1 UBC WBP4	117 interactors: ABTB1 ACTB ACVR1 AFF1 AP2A1 ARHGAP9 ARID1B ARNT ASB2 ASH2L BAZ1A BTG2 C10orf2 CAMSAP1 CEP135 CHPF CLPB CPXM2 CSH1 CSH2 CTR9 CXXC5 CYP11A1 DIAPH3 DKK1 DNAJA3 DNAJC7 DST DSTN E4F1 EIF3C EIF3E EIF3F ERVV-1 EVC2 EXPH5 FLI1 FN1 FTL GRN HEY1 HEYL HUWE1 KDM1A KDM6A KIAA0226 KMT2D LEMD3 LMO4 LNPEP LRP5 MAN1A2 MAN1C1 MAN2B1 MBD1 MCM3AP METAP1 MGAT1 MTMR10 MTMR11 NAGK OTUB1 PABPC4 PAPPA PELP1 PHKA2 PIR PKP2 PLEC PNPLA2 PPARD PPP2R5E PRMT6 PSAP PSMD8 QARS RANBP9 RFX1 RMND5A RNF123 RRBP1 SECISBP2 SF3B1 SIL1 SMAD2 SMAD3 SMAD4 SMG1 SNRNP70 SPTBN1 STAG1 SVEP1 TBCD TERF1 TINAGL1 TMEM57 TOB1 TRIM29 TRIP12 TTC37 UBA6 UBE3A UBQLN1 UBQLN4 UNC45A VCPIP1 VPS8 XAB2 YWHAQ ZEB2 ZNF484 ZNF557 ZNF587 ZNF587B ZNF592 ZNF83 ZSCAN4
Entrez ID		23451	4093
HPRD ID		09281	04484
Ensembl ID		ENSG00000115524	ENSG00000120693
Uniprot IDs		A0JLT9 O75533 Q7Z497	O15198
PDB IDs		2F9D 2F9J 2FHO 2PEH 3LQV
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Processing Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transforming Growth Factor Beta Receptor Signaling Pathway Phosphorylation Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription, DNA-templated Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development RNA Biosynthetic Process Osteoblast Fate Commitment Mullerian Duct Regression Regulation Of Nitrogen Compound Metabolic Process Kidney Epithelium Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Cycle Phosphate-containing Compound Metabolic Process Intracellular Signal Transduction Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process BMP Signaling Pathway Macromolecule Biosynthetic Process Midbrain Development Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Division Anatomical Structure Regression Signal Transduction By Phosphorylation Transcription From RNA Polymerase II Promoter Cellular Response To BMP Stimulus Enzyme Linked Receptor Protein Signaling Pathway Protein Phosphorylation Kidney Development Rhythmic Process	Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Gene Expression Cellular Metabolic Process Transcription, DNA-templated Biosynthetic Process RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Process Cellular Protein Metabolic Process Protein Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Gastrulation Anterior/posterior Pattern Specification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Developmental Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Atrioventricular Valve Morphogenesis Endoderm Development Nitrogen Compound Metabolic Process Formation Of Primary Germ Layer Cell Differentiation Atrioventricular Valve Development Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transcription From RNA Polymerase II Promoter Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Embryo Development Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process SMAD Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Pattern Specification Process
Tagcloud ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un
Tagcloud (Difference) ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un
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