SF3B1 and TCERG1

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vitro)

		SF3B1	TCERG1
Gene Name		splicing factor 3b, subunit 1, 155kDa	transcription elongation regulator 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nuclear Speck Catalytic Step 2 Spliceosome	Nucleus Nucleolus Actin Cytoskeleton
	Molecular Function	Chromatin Binding Protein Binding Poly(A) RNA Binding	RNA Polymerase II Repressing Transcription Factor Binding RNA Polymerase II Transcription Corepressor Activity Transcription Coactivator Activity Protein Binding Poly(A) RNA Binding Proline-rich Region Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Anterior/posterior Pattern Specification Gene Expression	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: APBB1 C11orf58 CALM1 CSNK2A1 DYRK1A ERG IL7R MELK MYC NUDT21 PLRG1 PPP1R8 PRPF40A RBM17 SF3B3 SF3B6 SMAD1 SMAD5 SMAD9 SNIP1 TCERG1 TOP1 UBC WBP4	52 interactors: ABI1 BARD1 BRD4 CHAF1A CHD3 CPSF6 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO1 TPM4 U2AF2 WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		23451	10915
HPRD ID		09281	10393
Ensembl ID		ENSG00000115524	ENSG00000113649
Uniprot IDs		A0JLT9 O75533 Q7Z497	O14776
PDB IDs		2F9D 2F9J 2FHO 2PEH 3LQV	2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2NNT 3HFH 4FQG
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Processing Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transforming Growth Factor Beta Receptor Signaling Pathway Phosphorylation Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription, DNA-templated Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development RNA Biosynthetic Process Osteoblast Fate Commitment Mullerian Duct Regression Regulation Of Nitrogen Compound Metabolic Process Kidney Epithelium Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Cycle Phosphate-containing Compound Metabolic Process Intracellular Signal Transduction Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process BMP Signaling Pathway Macromolecule Biosynthetic Process Midbrain Development Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Division Anatomical Structure Regression Signal Transduction By Phosphorylation Transcription From RNA Polymerase II Promoter Cellular Response To BMP Stimulus Enzyme Linked Receptor Protein Signaling Pathway Protein Phosphorylation Kidney Development Rhythmic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process MRNA 3'-splice Site Recognition Cellular Component Assembly MRNA Splice Site Selection Spliceosomal Complex Assembly Regulation Of RNA Splicing Cellular Macromolecular Complex Assembly Ribonucleoprotein Complex Assembly Cellular Metabolic Process Protein Complex Assembly Cellular Process Positive Regulation Of RNA Splicing Cellular Response To Stress Regulation Of MRNA Processing Actin Polymerization Or Depolymerization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To DNA Damage Stimulus Response To Stress DNA Repair Ribonucleoprotein Complex Biogenesis Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Transcription, DNA-templated Viral Process Phagocytosis Regulation Of Gene Expression Fc Receptor Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process MRNA 3'-end Processing Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Lamellipodium Morphogenesis Rhythmic Process Developmental Process
Tagcloud ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un	12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Difference) ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un	12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Intersection) ?