SF3B1 and RBM17

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SF3B1	RBM17
Gene Name		splicing factor 3b, subunit 1, 155kDa	RNA binding motif protein 17
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nuclear Speck Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex
	Molecular Function	Chromatin Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Anterior/posterior Pattern Specification Gene Expression	Alternative MRNA Splicing, Via Spliceosome
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Vitiligo ( 20410501)
Protein-Protein Interactions		24 interactors: APBB1 C11orf58 CALM1 CSNK2A1 DYRK1A ERG IL7R MELK MYC NUDT21 PLRG1 PPP1R8 PRPF40A RBM17 SF3B3 SF3B6 SMAD1 SMAD5 SMAD9 SNIP1 TCERG1 TOP1 UBC WBP4	17 interactors: APBB1 CCHCR1 CEP55 CSNK2A1 CWC15 DHX15 FAM9B GOLGA2 HINFP KIAA1683 PPP1R12C QRICH1 SAP30BP SAT1 SF1 SF3B1 U2SURP
Entrez ID		23451	84991
HPRD ID		09281	09501
Ensembl ID		ENSG00000115524	ENSG00000134453
Uniprot IDs		A0JLT9 O75533 Q7Z497	Q5W009 Q96I25
PDB IDs		2F9D 2F9J 2FHO 2PEH 3LQV	2PE8 2PEH
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Processing Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transforming Growth Factor Beta Receptor Signaling Pathway Phosphorylation Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription, DNA-templated Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development RNA Biosynthetic Process Osteoblast Fate Commitment Mullerian Duct Regression Regulation Of Nitrogen Compound Metabolic Process Kidney Epithelium Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Cycle Phosphate-containing Compound Metabolic Process Intracellular Signal Transduction Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process BMP Signaling Pathway Macromolecule Biosynthetic Process Midbrain Development Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Division Anatomical Structure Regression Signal Transduction By Phosphorylation Transcription From RNA Polymerase II Promoter Cellular Response To BMP Stimulus Enzyme Linked Receptor Protein Signaling Pathway Protein Phosphorylation Kidney Development Rhythmic Process See more	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process RNA Splicing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Processing Nitrogen Compound Metabolic Process MRNA Metabolic Process Negative Regulation Of Thymidylate Synthase Biosynthetic Process Cell Cycle Mitotic Cell Cycle Spermidine Acetylation Putrescine Catabolic Process Primary Sex Determination Cell Cycle Process Oxalate Transport MRNA 3'-splice Site Recognition Polyamine Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Negative Regulation Of Female Gonad Development See more
Tagcloud ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un
Tagcloud (Difference) ?		binet biology birc3 briefer chinese cll concurrent confounded consecutive descent diverse etiology european fludarabine frequencies germline give ighv insights lymphocytic mutated mutations myd88 notch1 persons predominately stratification tp53 un
Tagcloud (Intersection) ?