TCP10L and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		TCP10L	FBXO25
Gene Name		t-complex 10-like	F-box protein 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Protein Binding Identical Protein Binding Protein Self-association Repressing Transcription Factor Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP DAPK3 FBXO25 IKBKG MXD4 PMF1 TNNC1	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		140290	26260
HPRD ID		10518	16439
Ensembl ID			ENSG00000147364
Uniprot IDs		Q8TDR4 Q9NV44	Q8TCJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Smooth Muscle Contraction Regulation Of Muscle Filament Sliding Speed Synaptic Growth At Neuromuscular Junction Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Muscle Filament Sliding Regulation Of Myosin II Filament Organization Regulation Of Muscle Contraction Gene Expression Diaphragm Contraction Innate Immune Response Collateral Sprouting Axon Midline Choice Point Recognition Involuntary Skeletal Muscle Contraction Intracellular Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Apoptotic Process Programmed Cell Death Transcription, DNA-templated Negative Regulation Of ATPase Activity Cell Death Death Neuron Remodeling Regulation Of Translation RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Calcium Ion Homeostasis Regulation Of RNA Biosynthetic Process Calcium Ion Homeostasis Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Respiratory System Process Immune Response Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Defense Response Regulation Of Gene Expression Cellular Copper Ion Homeostasis Regulation Of Nitrogen Compound Metabolic Process Homeostatic Process Negative Regulation Of Hydrolase Activity Regulation Of Actin Filament-based Process Cellular Metal Ion Homeostasis Regulation Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
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