TCP10L and MXD4

Number of citations of the paper that reports this interaction (PubMedID 15469726)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TCP10L	MXD4
Description		t-complex 10 like	MAX dimerization protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding DNA-binding Transcription Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways			Nuclear signaling by ERBB4
Drugs
Diseases
GWAS			HDL cholesterol levels ( 32203549) Monocyte count ( 32888494)
Interacting Genes		33 interacting genes: APP CATSPERT CCDC102B CCDC57 CCDC70 CDR2L CIAO1 DAPK3 FBXO25 FHL2 FRS3 IKBKG LMO1 LMO2 LMO3 LRRK2 MAPK9 MFAP1 MXD4 NCK2 NTAQ1 NXF1 PMF1 PRPH RALBP1 SAAL1 SMARCD1 TCEANC TNNC1 TNS2 TRIM55 TRIM63 TSSK3	6 interacting genes: MAX MLX SHBG SIN3A SMC3 TCP10L
Entrez ID		140290	10608
HPRD ID		10518	10103
Ensembl ID		ENSG00000242220	ENSG00000123933
Uniprot IDs		Q8TDR4	Q14582
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To Manganese Ion Negative Regulation Of Response To Endoplasmic Reticulum Stress	Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Chromatin Cellular Response To Tert-butyl Hydroperoxide Response To Methylglyoxal Myc-Max Complex Negative Regulation Of RNA Metabolic Process Mad-Max Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Establishment Of Meiotic Sister Chromatid Cohesion Protein Dimerization Activity DNA-binding Transcription Factor Binding Androgen Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Meiotic Cohesin Complex Mediator Complex Binding Regulation Of Nucleobase-containing Compound Metabolic Process Cohesin Complex Establishment Of Mitotic Sister Chromatid Cohesion Mitotic Cohesin Complex Cellular Response To Dopamine Transcription Corepressor Activity Establishment Of Sister Chromatid Cohesion Response To Dopamine Negative Regulation Of Macromolecule Biosynthetic Process Cellular Response To Hydroperoxide DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of Biosynthetic Process Negative Regulation Of Circadian Rhythm Regulation Of Transcription By RNA Polymerase II Lateral Element Negative Regulation Of Macromolecule Metabolic Process Protein Heterodimerization Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Mitotic Sister Chromatid Cohesion Cellular Response To Catecholamine Stimulus Negative Regulation Of Metabolic Process Dynein Complex Binding Sin3-type Complex Response To Catecholamine Response To Hydroperoxide Cerebral Cortex Neuron Differentiation
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