TCP10L and CDR2L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCP10L	CDR2L
Description		t-complex 10 like	cerebellar degeneration related protein 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding Identical Protein Binding DNA-binding Transcription Factor Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Vesicle Transport Along Microtubule Golgi To Secretory Granule Transport
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756)
Interacting Genes		33 interacting genes: APP CATSPERT CCDC102B CCDC57 CCDC70 CDR2L CIAO1 DAPK3 FBXO25 FHL2 FRS3 IKBKG LMO1 LMO2 LMO3 LRRK2 MAPK9 MFAP1 MXD4 NCK2 NTAQ1 NXF1 PMF1 PRPH RALBP1 SAAL1 SMARCD1 TCEANC TNNC1 TNS2 TRIM55 TRIM63 TSSK3	61 interacting genes: ANKRD11 BFSP2 C1orf216 C4orf46 CCDC146 CCDC185 CCDC187 CCHCR1 COX5B DRC12 EHHADH ELOA FAIM FAM161A FAM161B FAM86C1P HDAC4 HSF2BP INO80B KRT31 KRTAP13-4 LENG1 MESD OIP5 PPP1R18 PRPF31 RASAL3 RASD1 REL RINT1 SCNM1 SH2D4A SPMIP6 SPRY1 STX11 SVIP TBRG4 TCEANC TCHP TCP10L TFIP11 TSGA10IP UBE2I USP7 WASHC1 ZBTB42 ZNF19 ZNF250 ZNF35 ZNF417 ZNF572 ZNF629 ZNF648 ZNF655 ZNF669 ZNF688 ZNF80 ZNF835 ZSCAN22 ZSCAN23 ZSCAN26
Entrez ID		140290	30850
HPRD ID		10518	11041
Ensembl ID		ENSG00000242220	ENSG00000109089
Uniprot IDs		Q8TDR4	Q86X02
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To Manganese Ion Negative Regulation Of Response To Endoplasmic Reticulum Stress	Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
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