RIOK3 and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		RIOK3	FBXO25
Gene Name		RIO kinase 3	F-box protein 25
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Phosphorylation Chromosome Segregation	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BCL2L11 CASP10 CDC42 CREB3L3 FBXO25 PAK2 UBC	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		8780	26260
HPRD ID		04659	16439
Ensembl ID		ENSG00000101782	ENSG00000147364
Uniprot IDs		B0YJ89 B4E1Q4 O14730	Q8TCJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Death Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Fc Receptor Signaling Pathway Positive Regulation Of Cell Cycle Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Stress Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Apoptotic Process Apoptotic Signaling Pathway Programmed Cell Death Immune System Process Cell Death Death Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Neuron Death Regulation Of Epidermal Growth Factor Receptor Signaling Pathway T Cell Costimulation Positive Regulation Of Protein Metabolic Process Regulation Of ERBB Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Cellular Metabolic Process Immune Response Positive Regulation Of Kinase Activity Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Viral Process Positive Regulation Of Transferase Activity T Cell Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Positive Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Immune Response Regulation Of Signaling Signal Transduction Antigen Receptor-mediated Signaling Pathway Regulation Of Proteolysis Submandibular Salivary Gland Formation Actin Filament Branching Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		adaptive adaptor adds antiviral blocks bridges bridging combat complexity cytosolic defense elicits gammaherpesvirus herpesvirus ifns innate interacts interferon interferons irf3 kinome limiting nucleic physically screens shaping stranded tbk1 transcriptome
Tagcloud (Difference) ?		adaptive adaptor adds antiviral blocks bridges bridging combat complexity cytosolic defense elicits gammaherpesvirus herpesvirus ifns innate interacts interferon interferons irf3 kinome limiting nucleic physically screens shaping stranded tbk1 transcriptome
Tagcloud (Intersection) ?