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HIST2H2AC and CTDP1
Number of citations of the paper that reports this interaction (PMID
15670829
)
17
Data Source:
BioGRID
(enzymatic study)
HIST2H2AC
CTDP1
Gene Name
histone cluster 2, H2ac
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleosome
Nucleus
Extracellular Vesicular Exosome
Spindle Pole
Nucleoplasm
Cytoplasm
Centrosome
Spindle
Actin Cytoskeleton
Midbody
Spindle Midzone
Molecular Function
Molecular_function
DNA Binding
Protein Heterodimerization Activity
DNA-directed RNA Polymerase Activity
CTD Phosphatase Activity
Biological Process
Biological_process
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Protein Dephosphorylation
Exit From Mitosis
Gene Expression
Viral Process
Positive Regulation Of Viral Transcription
Cell Division
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Schizophrenia (
23212062
)
Protein-Protein Interactions
65 interactors:
ANP32A
ATXN7L3
BAP1
BARD1
BAZ1B
BMI1
BRCA1
CDY1
CHFR
COPRS
CRP
CTCFL
CTDP1
DDB2
DNMT3L
EIF2AK2
EP300
GATAD2A
GATAD2B
HAT1
HDAC2
HIST1H2BA
HIST1H3A
HIST1H4A
HIST2H2BE
HIST2H4A
KAT2A
KAT2B
KAT5
KAT7
MSL2
MYSM1
NAP1L4
NCAPH
NCL
NPM1
PARP10
PBRM1
PELP1
PRMT5
PRMT7
RAG1
RBBP4
RCC1
RNF168
RNF2
RNF20
RNF8
SART3
SIRT7
SSRP1
TAF15
TAF1A
TAF1B
TCF20
TSPY1
TSSK6
UBC
UBE2B
UBR2
UIMC1
USP12
USP16
USP22
USP46
42 interactors:
CDK7
CDK8
CDK9
CSNK2A1
CSNK2A2
CSNK2B
E2F1
ELP2
ELP3
ERH
GTF2F1
HIST1H4A
HIST2H2AC
INTS1
INTS3
INTS6
INTS7
INTS8
MED1
MED14
MED15
MED16
MED17
MED23
MED24
MED25
MED26
MED4
MED6
MED7
MED8
NDRG2
POLR2A
POLR2B
PRKDC
PRMT5
SNRNP70
SNRPB
STK38
TCEA1
UPP1
WDR77
Entrez ID
8338
9150
HPRD ID
09107
05377
Ensembl ID
ENSG00000184260
ENSG00000060069
Uniprot IDs
Q16777
Q9Y5B0
PDB IDs
1J2X
1ONV
2K7L
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromosome Organization
Chromatin Modification
Histone Modification
Organelle Organization
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Protein Modification Process
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Histone Ubiquitination
Regulation Of Gene Expression, Epigenetic
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
DNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Cellular Protein Metabolic Process
Gene Expression
Chromatin Remodeling
Regulation Of Metabolic Process
Chromatin Silencing
Cellular Metabolic Process
DNA Packaging
Nucleosome Organization
Protein Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Chromatin Assembly Or Disassembly
Negative Regulation Of Nucleic Acid-templated Transcription
Histone H2A Ubiquitination
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression, Epigenetic
Histone Acetylation
Nucleosome Assembly
RNA Metabolic Process
Protein-DNA Complex Assembly
Internal Peptidyl-lysine Acetylation
Negative Regulation Of Cellular Metabolic Process
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Negative Regulation Of Biosynthetic Process
Cell Cycle
Histone Deubiquitination
Chromatin Assembly
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Transcription, DNA-templated
Gene Expression
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Androgen Receptor Signaling Pathway
Regulation Of RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
DNA-templated Transcription, Elongation
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Viral Transcription
NcRNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
SnRNA Processing
Regulation Of Viral Transcription
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Process
Stem Cell Maintenance
SnRNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cell Cycle Checkpoint
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Stem Cell Development
Positive Regulation Of Metabolic Process
7-methylguanosine MRNA Capping
Regulation Of Viral Process
Tagcloud
?
13q14
18qtel
1p32
3p14
3q21
4q11
4q24
5p13
5p15
5ptel
8p23
9qtel
c84c11
cgh
d1s427
d5s23
d8s504
d9s325
dab2
dxs7132
faf1
fhit
genosensor
imbalances
q12
rbp1
rbp2
shgc
xq12
Tagcloud (Difference)
?
13q14
18qtel
1p32
3p14
3q21
4q11
4q24
5p13
5p15
5ptel
8p23
9qtel
c84c11
cgh
d1s427
d5s23
d8s504
d9s325
dab2
dxs7132
faf1
fhit
genosensor
imbalances
q12
rbp1
rbp2
shgc
xq12
Tagcloud (Intersection)
?