HIST2H2AC and SART3

Number of citations of the paper that reports this interaction (PMID 24526689)
0

Data Source:
BioGRID (pull down, pull down)

		HIST2H2AC	SART3
Gene Name		histone cluster 2, H2ac	squamous cell carcinoma antigen recognized by T cells 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Extracellular Vesicular Exosome	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP U4atac/U6atac SnRNP
	Molecular Function	Molecular_function DNA Binding Protein Heterodimerization Activity	Nucleotide Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Histone Binding Poly(A) RNA Binding Ubiquitin-specific Protease Binding
	Biological Process	Biological_process	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Cell Morphogenesis Nucleosome Assembly Regulation Of Gene Expression Homeostasis Of Number Of Cells Hematopoietic Stem Cell Proliferation Positive Regulation Of Histone Deubiquitination
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase Regulatory RNA pathways RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression Packaging Of Telomere Ends Telomere Maintenance Nucleosome assembly RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance HDACs deacetylate histones Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Meiotic synapsis Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression PRC2 methylates histones and DNA Cell Cycle, Mitotic RMTs methylate histone arginines Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions		65 interactors: ANP32A ATXN7L3 BAP1 BARD1 BAZ1B BMI1 BRCA1 CDY1 CHFR COPRS CRP CTCFL CTDP1 DDB2 DNMT3L EIF2AK2 EP300 GATAD2A GATAD2B HAT1 HDAC2 HIST1H2BA HIST1H3A HIST1H4A HIST2H2BE HIST2H4A KAT2A KAT2B KAT5 KAT7 MSL2 MYSM1 NAP1L4 NCAPH NCL NPM1 PARP10 PBRM1 PELP1 PRMT5 PRMT7 RAG1 RBBP4 RCC1 RNF168 RNF2 RNF20 RNF8 SART3 SIRT7 SSRP1 TAF15 TAF1A TAF1B TCF20 TSPY1 TSSK6 UBC UBE2B UBR2 UIMC1 USP12 USP16 USP22 USP46	12 interactors: AR C6 COIL HIST2H2AC HIST2H2BE KPNA2 LSM7 MEGF10 PRPF3 RNPS1 USP15 USP4
Entrez ID		8338	9733
HPRD ID		09107	11532
Ensembl ID		ENSG00000184260	ENSG00000075856
Uniprot IDs		Q16777	B7ZKM0 Q15020
PDB IDs			2DO4
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromosome Organization Chromatin Modification Histone Modification Organelle Organization Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Histone Ubiquitination Regulation Of Gene Expression, Epigenetic Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process DNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Cellular Protein Metabolic Process Gene Expression Chromatin Remodeling Regulation Of Metabolic Process Chromatin Silencing Cellular Metabolic Process DNA Packaging Nucleosome Organization Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Chromatin Assembly Or Disassembly Negative Regulation Of Nucleic Acid-templated Transcription Histone H2A Ubiquitination Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Histone Acetylation Nucleosome Assembly RNA Metabolic Process Protein-DNA Complex Assembly Internal Peptidyl-lysine Acetylation Negative Regulation Of Cellular Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Negative Regulation Of Biosynthetic Process Cell Cycle Histone Deubiquitination Chromatin Assembly	RNA Splicing Spliceosomal Tri-snRNP Complex Assembly MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly Cellular Macromolecule Catabolic Process Negative Regulation Of Integrin Biosynthetic Process Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Cell Proliferation Histone H2B Conserved C-terminal Lysine Deubiquitination Skeletal Muscle Satellite Cell Activation Protein Deubiquitination Protein Modification By Small Protein Removal Positive Regulation Of Integrin Biosynthetic Process Positive Regulation Of Activation Of Membrane Attack Complex Regulation Of Integrin Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Cellular Macromolecular Complex Assembly Ribonucleoprotein Complex Assembly Skeletal Muscle Satellite Cell Differentiation RNA Catabolic Process Recognition Of Apoptotic Cell Regulation Of Proteasomal Protein Catabolic Process Monoubiquitinated Protein Deubiquitination Positive Regulation Of Transcription From RNA Polymerase III Promoter Humoral Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Pathway-restricted SMAD Protein Phosphorylation Nuclear Transport Catabolic Process Positive Regulation Of Humoral Immune Response
Tagcloud ?			a24 alleles antigen antigens attempted bc cd8 ctls efficiently enhancer epitope ezh2735 hla homolog igg immunotherapy leukocyte mononuclear mrp3 mrp31293 multidrug panel peptides polycomb reactive rejection thereafter zeste
Tagcloud (Difference) ?			a24 alleles antigen antigens attempted bc cd8 ctls efficiently enhancer epitope ezh2735 hla homolog igg immunotherapy leukocyte mononuclear mrp3 mrp31293 multidrug panel peptides polycomb reactive rejection thereafter zeste
Tagcloud (Intersection) ?