CTDP1 and MED7

Number of citations of the paper that reports this interaction (PMID 16239144)
97

Data Source:
BioGRID (pull down)

		CTDP1	MED7
Gene Name		CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	mediator complex subunit 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Spindle Actin Cytoskeleton Midbody Spindle Midzone	Nucleus Nucleoplasm Transcription Factor Complex Mitochondrion Mediator Complex Nuclear Membrane
	Molecular Function	DNA-directed RNA Polymerase Activity CTD Phosphatase Activity	RNA Polymerase II Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Protein Dephosphorylation Exit From Mitosis Gene Expression Viral Process Positive Regulation Of Viral Transcription Cell Division	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Schizophrenia ( 23212062)
Protein-Protein Interactions		42 interactors: CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 HIST1H4A HIST2H2AC INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED14 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 WDR77	22 interactors: CTDP1 ESR1 ESR2 HAUS1 HGS HNF4A IKBKG LZTR1 MED22 MED31 MED8 MED9 PCBD2 PML RBFOX2 RELA RHOXF2 SREBF1 TRIM15 TRIM29 UBE2I ZSCAN1
Entrez ID		9150	9443
HPRD ID		05377	05439
Ensembl ID		ENSG00000060069	ENSG00000155868
Uniprot IDs		Q9Y5B0	O43513 Q6IAZ5
PDB IDs		1J2X 1ONV 2K7L
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Androgen Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Viral Transcription NcRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process SnRNA Processing Regulation Of Viral Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process Stem Cell Maintenance SnRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Stem Cell Development Positive Regulation Of Metabolic Process 7-methylguanosine MRNA Capping Regulation Of Viral Process	Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Intracellular Estrogen Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Cellular Process Negative Regulation Of Gene Expression Regulation Of Cell Proliferation Cellular Response To Lipid Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Type I Interferon Production Response To Steroid Hormone Vagina Development Uterus Development Negative Regulation Of Viral Release From Host Cell Steroid Hormone Mediated Signaling Pathway Viral Process Regulation Of Type I Interferon Production Negative Regulation Of Biosynthetic Process Cellular Response To Hormone Stimulus Positive Regulation Of Histone Deacetylation Rhythmic Process Female Genitalia Development Regulation Of Signaling
Tagcloud ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	1h agarose batch bead beads biotinylated centrifugation coactivators comprising concurrently cyclooxygenase detecting enhancer ester evaluating immunoblots incubated pcaf pellet pellets phorbol pulldown room srb7 streptavidin tfii trace transactivators washed
Tagcloud (Difference) ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	1h agarose batch bead beads biotinylated centrifugation coactivators comprising concurrently cyclooxygenase detecting enhancer ester evaluating immunoblots incubated pcaf pellet pellets phorbol pulldown room srb7 streptavidin tfii trace transactivators washed
Tagcloud (Intersection) ?