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HIST2H2AC and NAP1L4
Number of citations of the paper that reports this interaction (PMID
11073993
)
42
Data Source:
BioGRID
(pull down)
HIST2H2AC
NAP1L4
Gene Name
histone cluster 2, H2ac
nucleosome assembly protein 1-like 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleosome
Nucleus
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Molecular Function
Molecular_function
DNA Binding
Protein Heterodimerization Activity
Protein Binding
Poly(A) RNA Binding
Unfolded Protein Binding
Biological Process
Biological_process
Nucleosome Assembly
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Calcium levels (
20705733
)
Protein-Protein Interactions
65 interactors:
ANP32A
ATXN7L3
BAP1
BARD1
BAZ1B
BMI1
BRCA1
CDY1
CHFR
COPRS
CRP
CTCFL
CTDP1
DDB2
DNMT3L
EIF2AK2
EP300
GATAD2A
GATAD2B
HAT1
HDAC2
HIST1H2BA
HIST1H3A
HIST1H4A
HIST2H2BE
HIST2H4A
KAT2A
KAT2B
KAT5
KAT7
MSL2
MYSM1
NAP1L4
NCAPH
NCL
NPM1
PARP10
PBRM1
PELP1
PRMT5
PRMT7
RAG1
RBBP4
RCC1
RNF168
RNF2
RNF20
RNF8
SART3
SIRT7
SSRP1
TAF15
TAF1A
TAF1B
TCF20
TSPY1
TSSK6
UBC
UBE2B
UBR2
UIMC1
USP12
USP16
USP22
USP46
10 interactors:
CSNK2A1
CSNK2A2
EP300
HIST1H1A
HIST1H2AE
HIST2H2AC
HIST2H2BE
HIST2H3C
HIST2H4A
HIST3H3
Entrez ID
8338
4676
HPRD ID
09107
11873
Ensembl ID
ENSG00000184260
ENSG00000205531
Uniprot IDs
Q16777
F5HFY4
Q99733
PDB IDs
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromosome Organization
Chromatin Modification
Histone Modification
Organelle Organization
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Protein Modification Process
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Histone Ubiquitination
Regulation Of Gene Expression, Epigenetic
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
DNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Cellular Protein Metabolic Process
Gene Expression
Chromatin Remodeling
Regulation Of Metabolic Process
Chromatin Silencing
Cellular Metabolic Process
DNA Packaging
Nucleosome Organization
Protein Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Chromatin Assembly Or Disassembly
Negative Regulation Of Nucleic Acid-templated Transcription
Histone H2A Ubiquitination
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression, Epigenetic
Histone Acetylation
Nucleosome Assembly
RNA Metabolic Process
Protein-DNA Complex Assembly
Internal Peptidyl-lysine Acetylation
Negative Regulation Of Cellular Metabolic Process
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Negative Regulation Of Biosynthetic Process
Cell Cycle
Histone Deubiquitination
Chromatin Assembly
DNA Methylation On Cytosine
Nucleosome Assembly
Chromatin Silencing At RDNA
Chromatin Assembly
Nucleosome Organization
Chromosome Organization
Chromatin Assembly Or Disassembly
Protein-DNA Complex Assembly
DNA Packaging
Chromatin Silencing
Mitotic Spindle Checkpoint
Negative Regulation Of Chromosome Segregation
Chromatin Organization
Mitotic Cell Cycle
DNA Conformation Change
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Metaphase/anaphase Transition
DNA Methylation
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Histone H2B Acetylation
Negative Regulation Of Cellular Protein Catabolic Process
Telomere Maintenance
Negative Regulation Of Cell Division
Regulation Of Chromosome Segregation
DNA Modification
Negative Regulation Of Chromosome Organization
Gene Silencing
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Protein Catabolic Process
Regulation Of Mitotic Nuclear Division
N-terminal Peptidyl-lysine Acetylation
Histone H4-K20 Demethylation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Cellular Macromolecular Complex Assembly
Negative Regulation Of Megakaryocyte Differentiation
Regulation Of Tubulin Deacetylation
Mitotic Cell Cycle Checkpoint
Mitotic Cell Cycle Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Chromosome Organization
Regulation Of Gene Expression, Epigenetic
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Tagcloud
?
11p15
approved
cloning
competition
cooh
deduced
demonstrates
etiology
g401
hgmw
histones
intron
linker
mutagenesis
mutational
naked
nh3
nucleosome
onto
packaging
positional
shuttle
subcellular
symbol
templates
wilms
wt
wts
Tagcloud (Difference)
?
11p15
approved
cloning
competition
cooh
deduced
demonstrates
etiology
g401
hgmw
histones
intron
linker
mutagenesis
mutational
naked
nh3
nucleosome
onto
packaging
positional
shuttle
subcellular
symbol
templates
wilms
wt
wts
Tagcloud (Intersection)
?