CTDP1 and INTS6

Number of citations of the paper that reports this interaction (PubMedID 16239144)
0

Data Source:
BioGRID (pull down)

		CTDP1	INTS6
Description		CTD phosphatase subunit 1	integrator complex subunit 6
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Spindle Cytoskeleton Midbody Protein-containing Complex Spindle Midzone	Chromatin Nucleus Nucleoplasm Chromosome Actin Cytoskeleton Integrator Complex INTAC Complex
	Molecular Function	TFIIF-class Transcription Factor Complex Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Hydrolase Activity Tat Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Protein Dephosphorylation Exit From Mitosis Host-mediated Activation Of Viral Transcription Cell Division Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development	Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II SnRNA 3'-end Processing Protein Localization To Chromatin RNA Polymerase II Transcription Initiation Surveillance
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Cerebrospinal P-tau181p levels ( 28247064) Metabolite levels ( 23823483) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 32888494) Schizophrenia ( 23212062) Smoking initiation (ever regular vs never regular) ( 30679032)	Amyotrophic lateral sclerosis (sporadic) ( 24529757)
Interacting Genes		41 interacting genes: AKT1 CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 USP7 WDR77	2 interacting genes: CTDP1 MCM7
Entrez ID		9150	26512
HPRD ID		05377	05063
Ensembl ID		ENSG00000060069	ENSG00000102786
Uniprot IDs		Q9Y5B0	B3KU90 Q9UL03
PDB IDs		1J2X 1ONV 2K7L	7BV7 7CUN 7PKS 7YCX 8RBX 8RBZ 8RC4 8YJB
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Elongation Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly RNA Metabolic Process Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Nucleoplasm Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Initiation Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Protein-DNA Complex Assembly Nucleobase-containing Compound Biosynthetic Process Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Initiation Surveillance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Elongation By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Transcription Coregulator Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-templated Transcription Elongation Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Vitamin D Receptor Binding DNA-templated Transcription Nuclear RNA Surveillance Positive Regulation Of Biosynthetic Process INTAC Complex RNA Surveillance DNA-templated Transcription Initiation	CMG Complex Double-strand Break Repair Via Break-induced Replication DNA Strand Elongation Involved In DNA Replication Single-stranded DNA Helicase Activity Regulation Of DNA-templated DNA Replication Initiation DNA Strand Elongation MCM Complex Tat Protein Binding TFIIF-class Transcription Factor Complex Binding Host-mediated Activation Of Viral Transcription Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Exit From Mitosis DNA Replication Initiation Negative Regulation Of Cardiac Muscle Tissue Growth Spindle Midzone Host-mediated Perturbation Of Viral Transcription DNA Helicase Activity Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Muscle Hypertrophy Host-mediated Activation Of Viral Process Negative Regulation Of Organ Growth Negative Regulation Of Cardiac Muscle Hypertrophy Cellular Response To Epidermal Growth Factor Stimulus Transcription Elongation By RNA Polymerase II Response To Epidermal Growth Factor DNA-templated Transcription Elongation Hydrolase Activity Cellular Response To Xenobiotic Stimulus Regulation Of Heart Growth Host-mediated Perturbation Of Viral Process Negative Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Regulation Of Striated Muscle Cell Differentiation Regulation Of Organ Growth Negative Regulation Of Developmental Growth Single-stranded DNA Binding Host-mediated Perturbation Of Symbiont Process Regulation Of DNA Replication Nucleic Acid Metabolic Process Modulation Of Process Of Another Organism Helicase Activity Dephosphorylation Double-strand Break Repair Via Homologous Recombination Phosphoprotein Phosphatase Activity Recombinational Repair DNA Replication
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