CTDP1 and ELP3

Number of citations of the paper that reports this interaction (PMID 11818576)
39

Data Source:
BioGRID (pull down)

		CTDP1	ELP3
Gene Name		CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	elongator acetyltransferase complex subunit 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Spindle Actin Cytoskeleton Midbody Spindle Midzone	Histone Acetyltransferase Complex Nucleolus Cytoplasm Transcription Elongation Factor Complex Elongator Holoenzyme Complex
	Molecular Function	DNA-directed RNA Polymerase Activity CTD Phosphatase Activity	RNA Polymerase II Core Binding Protein Binding Phosphorylase Kinase Regulator Activity H3 Histone Acetyltransferase Activity H4 Histone Acetyltransferase Activity Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Protein Dephosphorylation Exit From Mitosis Gene Expression Viral Process Positive Regulation Of Viral Transcription Cell Division	Neuron Migration TRNA Wobble Uridine Modification Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Central Nervous System Development Positive Regulation Of Cell Migration Histone H3 Acetylation Histone H4 Acetylation Regulation Of Protein Kinase Activity
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Schizophrenia ( 23212062)
Protein-Protein Interactions		42 interactors: CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 HIST1H4A HIST2H2AC INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED14 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 WDR77	6 interactors: CTDP1 HIST1H4A HIST2H3C IKBKAP SMAD1 SMURF1
Entrez ID		9150	55140
HPRD ID		05377	10936
Ensembl ID		ENSG00000060069	ENSG00000134014
Uniprot IDs		Q9Y5B0	Q9H9T3
PDB IDs		1J2X 1ONV 2K7L
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Androgen Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Viral Transcription NcRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process SnRNA Processing Regulation Of Viral Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process Stem Cell Maintenance SnRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Stem Cell Development Positive Regulation Of Metabolic Process 7-methylguanosine MRNA Capping Regulation Of Viral Process	Gene Silencing DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Expression, Epigenetic Chromatin Silencing Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Methylation Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression, Epigenetic BMP Signaling Pathway DNA-templated Transcription, Elongation DNA Modification Cellular Protein Modification Process Gene Expression Transforming Growth Factor Beta Receptor Signaling Pathway Histone H4-K20 Demethylation Cellular Response To Transforming Growth Factor Beta Stimulus Transcription From RNA Polymerase II Promoter Response To Transforming Growth Factor Beta Regulation Of Ossification Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Nucleobase-containing Compound Metabolic Process Primary MiRNA Processing Protein Complex Assembly Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Osteoblast Fate Commitment Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Replication-dependent Nucleosome Assembly Exit From Mitosis SMAD Protein Complex Assembly Negative Regulation Of Gene Expression Nitrogen Compound Metabolic Process Protein Metabolic Process Mesodermal Cell Fate Commitment Methylation Regulation Of Megakaryocyte Differentiation Protein Localization To Cell Surface Receptor Catabolic Process Cardiac Muscle Cell Proliferation
Tagcloud ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	aberrant alternative arrdc3 carcinomas cpg detect ductal explore follows frequency gata5 grades hypermethylation idcs inactivate inactivation islands lower lymph matched methylated methylation mnts node pax6 promoter represents suppressor unmethylated
Tagcloud (Difference) ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	aberrant alternative arrdc3 carcinomas cpg detect ductal explore follows frequency gata5 grades hypermethylation idcs inactivate inactivation islands lower lymph matched methylated methylation mnts node pax6 promoter represents suppressor unmethylated
Tagcloud (Intersection) ?