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HIST2H2AC and BAZ1B
Number of citations of the paper that reports this interaction (PMID
16252006
)
31
Data Source:
BioGRID
(pull down)
HIST2H2AC
BAZ1B
Gene Name
histone cluster 2, H2ac
bromodomain adjacent to zinc finger domain, 1B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleosome
Nucleus
Extracellular Vesicular Exosome
Condensed Chromosome
Pericentric Heterochromatin
Nuclear Replication Fork
Molecular Function
Molecular_function
DNA Binding
Protein Heterodimerization Activity
Chromatin Binding
Protein Tyrosine Kinase Activity
Non-membrane Spanning Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Histone Kinase Activity
Lysine-acetylated Histone Binding
Vitamin D Receptor Activator Activity
Biological Process
Biological_process
Heart Morphogenesis
Double-strand Break Repair
Chromatin Assembly Or Disassembly
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Cellular Response To DNA Damage Stimulus
Histone Phosphorylation
Peptidyl-tyrosine Phosphorylation
Chromatin-mediated Maintenance Of Transcription
Positive Regulation Of Receptor Activity
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Hypertriglyceridemia (
23505323
)
Protein C levels (
20802025
)
Triglycerides (
20864672
)
Urate levels (
23263486
)
Protein-Protein Interactions
65 interactors:
ANP32A
ATXN7L3
BAP1
BARD1
BAZ1B
BMI1
BRCA1
CDY1
CHFR
COPRS
CRP
CTCFL
CTDP1
DDB2
DNMT3L
EIF2AK2
EP300
GATAD2A
GATAD2B
HAT1
HDAC2
HIST1H2BA
HIST1H3A
HIST1H4A
HIST2H2BE
HIST2H4A
KAT2A
KAT2B
KAT5
KAT7
MSL2
MYSM1
NAP1L4
NCAPH
NCL
NPM1
PARP10
PBRM1
PELP1
PRMT5
PRMT7
RAG1
RBBP4
RCC1
RNF168
RNF2
RNF20
RNF8
SART3
SIRT7
SSRP1
TAF15
TAF1A
TAF1B
TCF20
TSPY1
TSSK6
UBC
UBE2B
UBR2
UIMC1
USP12
USP16
USP22
USP46
15 interactors:
CDT1
HIST1H3A
HIST1H4A
HIST2H2AC
HIST2H2BE
MAPK14
MAPK3
MAPK9
MYO1C
NR4A2
PCNA
SMARCA1
SMARCA5
SMARCC2
SMARCE1
Entrez ID
8338
9031
HPRD ID
09107
10416
Ensembl ID
ENSG00000184260
ENSG00000009954
Uniprot IDs
Q16777
Q9UIG0
PDB IDs
1F62
Enriched GO Terms of Interacting Partners
?
Chromatin Organization
Chromosome Organization
Chromatin Modification
Histone Modification
Organelle Organization
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Protein Modification Process
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Histone Ubiquitination
Regulation Of Gene Expression, Epigenetic
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
DNA Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Cellular Protein Metabolic Process
Gene Expression
Chromatin Remodeling
Regulation Of Metabolic Process
Chromatin Silencing
Cellular Metabolic Process
DNA Packaging
Nucleosome Organization
Protein Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Chromatin Assembly Or Disassembly
Negative Regulation Of Nucleic Acid-templated Transcription
Histone H2A Ubiquitination
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression, Epigenetic
Histone Acetylation
Nucleosome Assembly
RNA Metabolic Process
Protein-DNA Complex Assembly
Internal Peptidyl-lysine Acetylation
Negative Regulation Of Cellular Metabolic Process
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Negative Regulation Of Biosynthetic Process
Cell Cycle
Histone Deubiquitination
Chromatin Assembly
Nucleosome Organization
ATP-dependent Chromatin Remodeling
Chromatin Assembly Or Disassembly
Chromosome Organization
Chromatin Remodeling
Chromatin Organization
Chromatin Silencing At RDNA
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleosome Assembly
Chromatin Silencing
Chromatin Assembly
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organelle Organization
Protein-DNA Complex Assembly
DNA Packaging
Regulation Of Transcription From RNA Polymerase II Promoter
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Negative Regulation Of Gene Expression, Epigenetic
DNA Replication-dependent Nucleosome Assembly
Toll-like Receptor 4 Signaling Pathway
DNA Conformation Change
Chromatin Modification
DNA Metabolic Process
DNA Methylation On Cytosine
Gene Silencing
Nucleosome Disassembly
Toll-like Receptor Signaling Pathway
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Nitrogen Compound Metabolic Process
Response To Stress
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Transcription, DNA-templated
Activation Of Innate Immune Response
Tagcloud
?
ac
accessible
architecture
attenuates
clarify
cytoprotective
foci
gammah2ax
h2ax
h3k56
h3k9
hubs
integrated
ints3
irradiation
isoform
mark
matrix
mount
prevents
proteomic
respond
runx
runx2
ruvbl2
scaffolding
subnuclear
supported
uv
Tagcloud (Difference)
?
ac
accessible
architecture
attenuates
clarify
cytoprotective
foci
gammah2ax
h2ax
h3k56
h3k9
hubs
integrated
ints3
irradiation
isoform
mark
matrix
mount
prevents
proteomic
respond
runx
runx2
ruvbl2
scaffolding
subnuclear
supported
uv
Tagcloud (Intersection)
?