CTDP1 and MED26

Number of citations of the paper that reports this interaction (PubMedID 16239144)
0

Data Source:
BioGRID (pull down)

		CTDP1	MED26
Description		CTD phosphatase subunit 1	mediator complex subunit 26
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GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Spindle Cytoskeleton Midbody Protein-containing Complex Spindle Midzone	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	TFIIF-class Transcription Factor Complex Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Hydrolase Activity Tat Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Protein Dephosphorylation Exit From Mitosis Host-mediated Activation Of Viral Transcription Cell Division Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development	Regulation Of Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA Polymerase II Transcription Elongation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Cerebrospinal P-tau181p levels ( 28247064) Metabolite levels ( 23823483) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 32888494) Schizophrenia ( 23212062) Smoking initiation (ever regular vs never regular) ( 30679032)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
Interacting Genes		41 interacting genes: AKT1 CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 USP7 WDR77	8 interacting genes: AURKA CDK8 CTDP1 MED12 MED8 MED9 RBP1 SREBF1
Entrez ID		9150	9441
HPRD ID		05377	05437
Ensembl ID		ENSG00000060069	ENSG00000105085
Uniprot IDs		Q9Y5B0	O95402
PDB IDs		1J2X 1ONV 2K7L	5ODD 6ZV3 7EMF 7ENA 7ENC 7ENJ 8GXQ 8GXS
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription, Elongation Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly RNA Metabolic Process Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Nucleoplasm Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Initiation Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Protein-DNA Complex Assembly Nucleobase-containing Compound Biosynthetic Process Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Initiation Surveillance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Elongation By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Transcription Coregulator Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-templated Transcription Elongation Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Vitamin D Receptor Binding DNA-templated Transcription Nuclear RNA Surveillance Positive Regulation Of Biosynthetic Process INTAC Complex RNA Surveillance DNA-templated Transcription Initiation	Mediator Complex CKM Complex Positive Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Transcription Coregulator Activity Spindle Midzone Core Mediator Complex Nucleoplasm Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Response To Metformin Positive Regulation Of DNA-templated Transcription, Elongation Transcription Preinitiation Complex Assembly Positive Regulation Of Metabolic Process Nucleus Positive Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Fatty Acid Metabolic Process Protein Modification Process TFIIF-class Transcription Factor Complex Binding Negative Regulation Of Developmental Growth Axis Elongation Involved In Somitogenesis Regulation Of Transcription Elongation By RNA Polymerase II All-trans-retinol Binding Sterol Response Element Binding Positive Regulation Of Oocyte Maturation Ubiquitin Ligase Complex Regulation Of DNA-templated Transcription Elongation Positive Regulation Of RNA Metabolic Process Spindle Assembly Involved In Female Meiosis I Germinal Vesicle Histone H3S10 Kinase Activity Regulation Of Ketone Metabolic Process Regulation Of Heart Rate By Chemical Signal Positive Regulation Of Lipid Metabolic Process Developmental Growth Involved In Morphogenesis GDF15-GFRAL Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Vitamin A Metabolic Process Retinoic Acid Biosynthetic Process Positive Regulation Of Small Molecule Metabolic Process Mitotic Cell Cycle Phase Transition
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