PIP4K2C and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		PIP4K2C	FBXO25
Gene Name		phosphatidylinositol-5-phosphate 4-kinase, type II, gamma	F-box protein 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Extracellular Vesicular Exosome	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	ATP Binding 1-phosphatidylinositol-5-phosphate 4-kinase Activity Identical Protein Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Phosphatidylinositol Phosphorylation	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 18794853)
Protein-Protein Interactions		3 interactors: APP BTK FBXO25	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		79837	26260
HPRD ID		15138	16439
Ensembl ID		ENSG00000166908	ENSG00000147364
Uniprot IDs		B3KQV3 Q8TBX8	Q8TCJ0
PDB IDs		2GK9
Enriched GO Terms of Interacting Partners?		Cell Maturation Regulation Of B Cell Cytokine Production Cellular Response To Molecule Of Fungal Origin Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Response To Molecule Of Fungal Origin Collateral Sprouting Axon Midline Choice Point Recognition Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Response To Oxidative Stress Neuron Remodeling Secretion By Cell Histamine Secretion By Mast Cell Histamine Secretion Positive Regulation Of B Cell Differentiation Secretion Histamine Transport Cellular Copper Ion Homeostasis Regulation Of B Cell Apoptotic Process Cell Activation Cellular Protein Modification Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Mast Cell Degranulation Innate Immune Response Production Of Molecular Mediator Involved In Inflammatory Response Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of B Cell Differentiation Mast Cell Mediated Immunity Mating Behavior Lysosome Localization Mast Cell Activation Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Peptidyl-tyrosine Autophosphorylation Apoptotic Process B Cell Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Fungus Leukocyte Degranulation Programmed Cell Death Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Death	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
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