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UBE2H and TRIM37
Number of citations of the paper that reports this interaction (PMID
19549727
)
40
Data Source:
BioGRID
(two hybrid)
UBE2H
TRIM37
Gene Name
ubiquitin-conjugating enzyme E2H
tripartite motif containing 37
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoplasm
Peroxisome
Cytosol
Aggresome
ESC/E(Z) Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Chromatin Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of NF-kappaB Transcription Factor Activity
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of Centriole Replication
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Aggresome Assembly
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
57 interactors:
BRAP
BYSL
CBLC
CD99
DTX3
DTX3L
DZIP3
EPS15
HDAC6
HIST2H2AA3
JADE1
LRSAM1
MARCH1
MARCH10
MARCH2
MARCH4
MARCH8
MKRN3
NEURL1
NHLRC1
POLL
POLM
RAG1
RELA
RNF10
RNF103
RNF113B
RNF114
RNF128
RNF133
RNF139
RNF144A
RNF146
RNF166
RNF185
RNF186
RNF2
RNF34
RNF38
RNF4
RNF6
STAM2
TRAIP
TRIM17
TRIM2
TRIM21
TRIM23
TRIM27
TRIM28
TRIM36
TRIM37
TRIM5
TRIM56
UBA1
UBASH3B
UBOX5
UBR2
59 interactors:
ANKRD11
APEX2
APTX
ARNT2
BYSL
CCDC33
CDC20B
CDK5RAP2
COPB1
CWF19L2
DDX6
DLGAP5
EWSR1
FAM107A
FAM124B
FAM161A
FAM50B
FXR2
KAT5
KIAA0408
KIF9
LTBR
MAGEB18
MCM10
MCRS1
NGFR
NUDT18
PBK
PNKP
PRC1
RASD1
RHPN1
RIBC2
RPL9
SCNM1
SSX2IP
TANK
TCEB3B
TNFRSF1B
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
UBASH3A
UBB
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2U
ZMAT2
ZNF329
ZNF417
ZNF655
Entrez ID
7328
4591
HPRD ID
03052
05463
Ensembl ID
ENSG00000186591
ENSG00000108395
Uniprot IDs
A4D1L5
P62256
A8K0V9
A8K8U4
F8WEE6
O94972
PDB IDs
2Z5D
3LRQ
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Protein Polyubiquitination
Protein Autoubiquitination
Cellular Metabolic Process
Negative Regulation Of Viral Release From Host Cell
Protein Monoubiquitination
Regulation Of Viral Release From Host Cell
Metabolic Process
Histone Ubiquitination
Protein Catabolic Process
Histone Monoubiquitination
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Negative Regulation Of Viral Process
Protein K63-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Histone H2A Ubiquitination
Histone H2A-K119 Monoubiquitination
Regulation Of Viral Entry Into Host Cell
Cellular Macromolecule Catabolic Process
Cellular Process
Negative Regulation Of Protein Metabolic Process
Histone Modification
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Viral Process
Regulation Of ERBB Signaling Pathway
Protein Trimerization
Aggresome Assembly
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein K6-linked Ubiquitination
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Histone H2A Monoubiquitination
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Chromatin Modification
Negative Regulation Of Cellular Protein Metabolic Process
Proteolysis
Catabolic Process
Somatic Hypermutation Of Immunoglobulin Genes
Somatic Diversification Of Immune Receptors Via Somatic Mutation
Negative Regulation Of Viral Entry Into Host Cell
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Polyubiquitination
TRIF-dependent Toll-like Receptor Signaling Pathway
Protein K48-linked Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Cellular Macromolecule Catabolic Process
Regulation Of Innate Immune Response
Protein K11-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein K63-linked Ubiquitination
Cellular Response To Stress
Catabolic Process
Polynucleotide 3' Dephosphorylation
Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of DNA-templated Transcription In Response To Stress
Programmed Cell Death
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Mitotic Cell Cycle Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cell Cycle Phase Transition
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Cell Death
Death
Activation Of NF-kappaB-inducing Kinase Activity
Modification-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Cellular Protein Catabolic Process
DNA Repair
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Stress-activated MAPK Cascade
NIK/NF-kappaB Signaling
Regulation Of NIK/NF-kappaB Signaling
Regulation Of Metabolic Process
Tagcloud
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0e
1426a
219g
3072g
abhd16a
abhd5
acp2
alms1
apoa2
atp1a2
bft
col14a1
ctsf
dars
decr1
ghrl
intron3
mc4r
mttp
nfkbia
nt5e
pfp
plat
ppp2r5d
rfc2
rragd
sdhd
serpinf1
tbc1d1
Tagcloud (Difference)
?
0e
1426a
219g
3072g
abhd16a
abhd5
acp2
alms1
apoa2
atp1a2
bft
col14a1
ctsf
dars
decr1
ghrl
intron3
mc4r
mttp
nfkbia
nt5e
pfp
plat
ppp2r5d
rfc2
rragd
sdhd
serpinf1
tbc1d1
Tagcloud (Intersection)
?