UBE2H and RNF144A

Number of citations of the paper that reports this interaction (PMID 19549727)
40

Data Source:
BioGRID (two hybrid)

		UBE2H	RNF144A
Gene Name		ubiquitin-conjugating enzyme E2H	ring finger protein 144A
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Golgi Apparatus Plasma Membrane Integral Component Of Membrane Cytoplasmic Vesicle Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity	Zinc Ion Binding Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Response to antipsychotic treatment ( 20195266)
Protein-Protein Interactions		57 interactors: BRAP BYSL CBLC CD99 DTX3 DTX3L DZIP3 EPS15 HDAC6 HIST2H2AA3 JADE1 LRSAM1 MARCH1 MARCH10 MARCH2 MARCH4 MARCH8 MKRN3 NEURL1 NHLRC1 POLL POLM RAG1 RELA RNF10 RNF103 RNF113B RNF114 RNF128 RNF133 RNF139 RNF144A RNF146 RNF166 RNF185 RNF186 RNF2 RNF34 RNF38 RNF4 RNF6 STAM2 TRAIP TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM28 TRIM36 TRIM37 TRIM5 TRIM56 UBA1 UBASH3B UBOX5 UBR2	13 interactors: E2F1 E2F2 E2F3 E2F4 PRKDC UBE2H UBE2K UBE2L3 UBE2L6 UBE2V1 UBE2V2 USP21 USP32
Entrez ID		7328	9781
HPRD ID		03052	11510
Ensembl ID		ENSG00000186591	ENSG00000151692
Uniprot IDs		A4D1L5 P62256	P50876
PDB IDs		2Z5D	1WIM
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Cellular Protein Metabolic Process Protein Metabolic Process Protein Polyubiquitination Protein Autoubiquitination Cellular Metabolic Process Negative Regulation Of Viral Release From Host Cell Protein Monoubiquitination Regulation Of Viral Release From Host Cell Metabolic Process Histone Ubiquitination Protein Catabolic Process Histone Monoubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Viral Process Protein K63-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Histone H2A Ubiquitination Histone H2A-K119 Monoubiquitination Regulation Of Viral Entry Into Host Cell Cellular Macromolecule Catabolic Process Cellular Process Negative Regulation Of Protein Metabolic Process Histone Modification Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Viral Process Regulation Of ERBB Signaling Pathway Protein Trimerization Aggresome Assembly Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein K6-linked Ubiquitination Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Histone H2A Monoubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Chromatin Modification Negative Regulation Of Cellular Protein Metabolic Process Proteolysis Catabolic Process Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Negative Regulation Of Viral Entry Into Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Protein Polyubiquitination Cellular Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Lens Fiber Cell Apoptotic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Positive Regulation Of Cellular Metabolic Process Catabolic Process Cellular Metabolic Process Apoptotic Signaling Pathway Mitotic Cell Cycle Positive Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Protein Catabolic Process Postreplication Repair Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Protein K11-linked Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Proteolysis Cellular Protein Metabolic Process Positive Regulation Of Gene Expression Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Protein K63-linked Ubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein K48-linked Ubiquitination Regulation Of Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Cellular Nitrogen Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To Stimulus Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Regulation Of Proteolysis Nitrogen Compound Metabolic Process Regulation Of DNA Repair Protein Metabolic Process
Tagcloud ?		0e 1426a 219g 3072g abhd16a abhd5 acp2 alms1 apoa2 atp1a2 bft col14a1 ctsf dars decr1 ghrl intron3 mc4r mttp nfkbia nt5e pfp plat ppp2r5d rfc2 rragd sdhd serpinf1 tbc1d1	catalytic cytoplasmic damage damaging dna e3 finger fingers induces insults interacts joining ligase ligases nonhomologous parc parkin persistent pk pkcs promotes prosurvival rbr reversed ring suffer ubiquitination vesicles
Tagcloud (Difference) ?		0e 1426a 219g 3072g abhd16a abhd5 acp2 alms1 apoa2 atp1a2 bft col14a1 ctsf dars decr1 ghrl intron3 mc4r mttp nfkbia nt5e pfp plat ppp2r5d rfc2 rragd sdhd serpinf1 tbc1d1	catalytic cytoplasmic damage damaging dna e3 finger fingers induces insults interacts joining ligase ligases nonhomologous parc parkin persistent pk pkcs promotes prosurvival rbr reversed ring suffer ubiquitination vesicles
Tagcloud (Intersection) ?