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UBE2H and RNF166
Number of citations of the paper that reports this interaction (PubMedID
19549727
)
29
Data Source:
BioGRID
(two hybrid)
UBE2H
RNF166
Description
ubiquitin conjugating enzyme E2 H
ring finger protein 166
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Cytoplasm
Molecular Function
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
Ubiquitin Conjugating Enzyme Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein Polyubiquitination
Immune System Process
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Protein Ubiquitination
Innate Immune Response
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Estimated glomerular filtration rate (
31152163
31451708
)
Lymphocyte count (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte count (
32888494
)
Response to antidepressants and depression (
27622933
)
White blood cell count (
32888494
)
Coffee consumption (
31046077
)
Hair color (
26926045
)
Interacting Genes
71 interacting genes:
BRAP
CBLC
CD99
CDK2
DTX3
DTX3L
DZIP3
EPS15
GID4
GOLGA2
H2AC18
H2AC20
HBP1
HDAC6
JADE1
LNX2
LRSAM1
MAEA
MARCHF1
MARCHF10
MARCHF2
MARCHF4
MARCHF8
MDM2
MKRN3
NEURL1
NEURL2
NHLRC1
POLL
POLM
PRKN
PSME3
RAG1
RBX1
RELA
RNF10
RNF103
RNF113B
RNF114
RNF128
RNF133
RNF139
RNF144A
RNF146
RNF166
RNF185
RNF186
RNF2
RNF34
RNF38
RNF4
RNF6
STAM2
STUB1
TLE5
TRAIP
TRIM13
TRIM17
TRIM2
TRIM23
TRIM28
TRIM36
TRIM37
TRIM5
TRIM56
TRIM69
TRIM72
UBASH3B
UBOX5
UBR2
UBR3
23 interacting genes:
CYLD
MAGEA1
MAGEC2
MKRN3
RNF41
SQSTM1
TRIM39
TRIM9
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2K
UBE2U
UBE2W
UBE2Z
USP2
XAF1
Entrez ID
7328
115992
HPRD ID
03052
15260
Ensembl ID
ENSG00000186591
ENSG00000158717
Uniprot IDs
A0A3B3IU20
A4D1L5
P62256
Q96A37
PDB IDs
2Z5D
8PJN
Enriched GO Terms of Interacting Partners
?
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Transferase Activity
Protein Modification Process
Zinc Ion Binding
Protein Metabolic Process
Protein Polyubiquitination
Metal Ion Binding
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Protein Autoubiquitination
Macromolecule Metabolic Process
Macromolecule Catabolic Process
Proteolysis
Protein Catabolic Process
Catabolic Process
Proteasomal Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin Ligase Complex
Protein Monoubiquitination
Ubiquitin Protein Ligase Binding
Protein K63-linked Ubiquitination
Autophagy
Positive Regulation Of Catabolic Process
Cytoplasm
Endoplasmic Reticulum Mannose Trimming
Protein K48-linked Ubiquitination
Regulation Of Protein Catabolic Process
Protein Alpha-1,2-demannosylation
Suppression Of Viral Release By Host
Immune System Process
Protein Deglycosylation
Aggresome Assembly
Innate Immune Response
Positive Regulation Of Protein Catabolic Process
ERAD Pathway
Endoplasmic Reticulum Quality Control Compartment
Cellular Response To Stress
Protein K6-linked Ubiquitination
Ubiquitin Binding
Inclusion Body Assembly
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Autophagy
Aggresome
Defense Response To Symbiont
Defense Response To Other Organism
Ubiquitin Conjugating Enzyme Activity
Post-translational Protein Modification
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Polyubiquitination
Protein Modification Process
Protein Metabolic Process
Proteolysis Involved In Protein Catabolic Process
Proteolysis
Modification-dependent Protein Catabolic Process
Macromolecule Catabolic Process
Ubiquitin-protein Transferase Activity
Protein K48-linked Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein K11-linked Ubiquitination
Macromolecule Metabolic Process
Transferase Activity
Catabolic Process
Protein Monoubiquitination
ATP Binding
Protein Catabolic Process
Ubiquitin Protein Ligase Activity
Nucleotide Binding
Proteasomal Protein Catabolic Process
Ubiquitin Protein Ligase Binding
Protein K63-linked Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Nucleus
ISG15 Transferase Activity
Negative Regulation Of Metabolic Process
ISG15-protein Conjugation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Protein Autoubiquitination
Programmed Cell Death
Cell Death
Molecular Sequestering Activity
Nucleoplasm
Protein K6-linked Ubiquitination
Cytosol
Apoptotic Process
Response To Interferon-beta
Negative Regulation Of Interleukin-18-mediated Signaling Pathway
Met1-linked Polyubiquitin Deubiquitinase Activity
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Type I Interferon Production
Negative Regulation Of Signal Transduction
Regulation Of Protein Ubiquitination
Negative Regulation Of Cell Communication
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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