TRIM37 and KIF9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIM37	KIF9
Gene Name		tripartite motif containing 37	kinesin family member 9
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Gene Ontology Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm	Podosome Cytoplasm Kinesin Complex Microtubule Vesicle
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Negative Regulation Of Centriole Replication Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly	Microtubule-based Movement Blood Coagulation Metabolic Process Extracellular Matrix Disassembly Regulation Of Podosome Assembly Organelle Disassembly
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Kinesins Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 23666239)
Protein-Protein Interactions		59 interactors: ANKRD11 APEX2 APTX ARNT2 BYSL CCDC33 CDC20B CDK5RAP2 COPB1 CWF19L2 DDX6 DLGAP5 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RPL9 SCNM1 SSX2IP TANK TCEB3B TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZMAT2 ZNF329 ZNF417 ZNF655	13 interactors: CARD9 EFHC2 IKZF1 JAKMIP2 KRTAP10-3 KRTAP10-9 LZTS2 PRMT6 ROPN1 SSX2IP TRIM27 TRIM37 ZBTB8A
Entrez ID		4591	64147
HPRD ID		05463	07444
Ensembl ID		ENSG00000108395	ENSG00000088727
Uniprot IDs		A8K0V9 A8K8U4 F8WEE6 O94972	A8K932 Q9HAQ2
PDB IDs		3LRQ	3NWN
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination TRIF-dependent Toll-like Receptor Signaling Pathway Protein K48-linked Ubiquitination MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Cellular Macromolecule Catabolic Process Regulation Of Innate Immune Response Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K63-linked Ubiquitination Cellular Response To Stress Catabolic Process Polynucleotide 3' Dephosphorylation Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Protein Catabolic Process Immune Response-regulating Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of DNA-templated Transcription In Response To Stress Programmed Cell Death I-kappaB Kinase/NF-kappaB Signaling Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To DNA Damage Stimulus Regulation Of Cell Cycle Phase Transition Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Cell Death Death Activation Of NF-kappaB-inducing Kinase Activity Modification-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of NIK/NF-kappaB Signaling Cellular Protein Catabolic Process DNA Repair Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Proteolysis Regulation Of Stress-activated MAPK Cascade NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Regulation Of Metabolic Process	Organelle Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Neutrophil Differentiation Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Histone H3-R2 Methylation Negative Regulation Of Interleukin-2 Secretion Chromatin Modification Histone H2A-K119 Monoubiquitination Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Centriole Replication Negative Regulation Of Calcium Ion Import Intraciliary Transport Involved In Cilium Morphogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Positive Regulation Of NK T Cell Differentiation Interferon-gamma Secretion Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Cellular Metabolic Process Spindle Midzone Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromosome Organization Regulation Of Centriole Replication Histone H2A Monoubiquitination Aggresome Assembly Regulation Of Cellular Process Response To Peptidoglycan Microtubule Severing Transcription, DNA-templated Histone H4-R3 Methylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cytoskeleton Organization RNA Biosynthetic Process Negative Regulation Of Viral Release From Host Cell Histone H2A Ubiquitination Negative Regulation Of Centrosome Duplication Peptidyl-arginine N-methylation Lymph Node Development Peyer's Patch Development Regulation Of Transcription, DNA-templated Regulation Of Tumor Necrosis Factor Biosynthetic Process Response To Muramyl Dipeptide Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
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