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UBE2H and POLL
Number of citations of the paper that reports this interaction (PubMedID
17588522
)
0
Data Source:
BioGRID
(enzymatic study)
UBE2H
POLL
Description
ubiquitin conjugating enzyme E2 H
DNA polymerase lambda
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Nucleus
Nucleoplasm
Chromosome
Site Of Double-strand Break
Molecular Function
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
Ubiquitin Conjugating Enzyme Activity
DNA Binding
DNA-directed DNA Polymerase Activity
Protein Binding
Transferase Activity
Nucleotidyltransferase Activity
Lyase Activity
DNA Polymerase Activity
Metal Ion Binding
5'-deoxyribose-5-phosphate Lyase Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Double-strand Break Repair Via Homologous Recombination
DNA Replication
DNA Repair
Base-excision Repair, Gap-filling
Nucleotide-excision Repair
Double-strand Break Repair Via Nonhomologous End Joining
DNA Damage Response
Somatic Hypermutation Of Immunoglobulin Genes
DNA Biosynthetic Process
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Estimated glomerular filtration rate (
31152163
31451708
)
Lymphocyte count (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte count (
32888494
)
Response to antidepressants and depression (
27622933
)
White blood cell count (
32888494
)
Interacting Genes
71 interacting genes:
BRAP
CBLC
CD99
CDK2
DTX3
DTX3L
DZIP3
EPS15
GID4
GOLGA2
H2AC18
H2AC20
HBP1
HDAC6
JADE1
LNX2
LRSAM1
MAEA
MARCHF1
MARCHF10
MARCHF2
MARCHF4
MARCHF8
MDM2
MKRN3
NEURL1
NEURL2
NHLRC1
POLL
POLM
PRKN
PSME3
RAG1
RBX1
RELA
RNF10
RNF103
RNF113B
RNF114
RNF128
RNF133
RNF139
RNF144A
RNF146
RNF166
RNF185
RNF186
RNF2
RNF34
RNF38
RNF4
RNF6
STAM2
STUB1
TLE5
TRAIP
TRIM13
TRIM17
TRIM2
TRIM23
TRIM28
TRIM36
TRIM37
TRIM5
TRIM56
TRIM69
TRIM72
UBASH3B
UBOX5
UBR2
UBR3
42 interacting genes:
APP
ATM
CCNDBP1
CDK1
CDK2
CMTM5
FAM9B
FSD2
GOLGA6L9
HMBOX1
HUWE1
KRT16
KRT19
KRT27
KRT40
KRTAP10-3
KRTAP10-7
LCN2
LDOC1
MAGEA12
MAGEA2
MAGEA2B
MAL2
MCC
MDFI
PCNA
PICK1
PNMA1
PRKD3
REV1
RPA1
SSX2IP
TFCP2
TFIP11
TNFRSF10D
TRIM23
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2H
ZRANB1
Entrez ID
7328
27343
HPRD ID
03052
09394
Ensembl ID
ENSG00000186591
ENSG00000166169
Uniprot IDs
A0A3B3IU20
A4D1L5
P62256
A8K860
B4DE17
Q5JQP8
Q9UGP5
PDB IDs
2Z5D
8PJN
1NZP
1RZT
1XSL
1XSN
1XSP
2BCQ
2BCR
2BCS
2BCU
2BCV
2GWS
2JW5
2PFN
2PFO
2PFP
2PFQ
3C5F
3C5G
3HW8
3HWT
3HX0
3MDA
3MDC
3MGH
3MGI
3PML
3PMN
3PNC
3UPQ
3UQ0
3UQ2
4FO6
4K4G
4K4H
4K4I
4X5V
4XA5
4XQ8
4XRH
4XUS
5CA7
5CB1
5CHG
5CJ7
5CP2
5CR0
5CWR
5DDM
5DDY
5DKW
5III
5IIJ
5IIK
5IIL
5IIM
5IIN
5IIO
5W4G
7M07
7M08
7M09
7M0A
7M0B
7M0C
7M0D
7M0E
7M43
7M44
7M45
7M46
7M47
7M48
7M49
7M4A
7M4B
7M4C
7M4D
7M4E
7M4F
7M4G
7M4H
7M4I
7M4J
7M4K
7M4L
7UN7
8U0O
Enriched GO Terms of Interacting Partners
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Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Transferase Activity
Protein Modification Process
Zinc Ion Binding
Protein Metabolic Process
Protein Polyubiquitination
Metal Ion Binding
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Protein Autoubiquitination
Macromolecule Metabolic Process
Macromolecule Catabolic Process
Proteolysis
Protein Catabolic Process
Catabolic Process
Proteasomal Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin Ligase Complex
Protein Monoubiquitination
Ubiquitin Protein Ligase Binding
Protein K63-linked Ubiquitination
Autophagy
Positive Regulation Of Catabolic Process
Cytoplasm
Endoplasmic Reticulum Mannose Trimming
Protein K48-linked Ubiquitination
Regulation Of Protein Catabolic Process
Protein Alpha-1,2-demannosylation
Suppression Of Viral Release By Host
Immune System Process
Protein Deglycosylation
Aggresome Assembly
Innate Immune Response
Positive Regulation Of Protein Catabolic Process
ERAD Pathway
Endoplasmic Reticulum Quality Control Compartment
Cellular Response To Stress
Protein K6-linked Ubiquitination
Ubiquitin Binding
Inclusion Body Assembly
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Autophagy
Aggresome
Defense Response To Symbiont
Defense Response To Other Organism
Ubiquitin Conjugating Enzyme Activity
Telomere Maintenance
Chromosome, Telomeric Region
Keratin Filament
Protein K48-linked Ubiquitination
Telomere Organization
Ubiquitin-protein Transferase Activity
DNA Biosynthetic Process
Intermediate Filament
Post-translational Protein Modification
Protein Polyubiquitination
Nucleus
DNA Metabolic Process
Protein Monoubiquitination
Structural Constituent Of Skin Epidermis
Cellular Senescence
Cyclin-dependent Protein Kinase Activity
Chromosome Organization
DNA Repair
DNA Replication
Intermediate Filament Organization
Protein Localization To Site Of Double-strand Break
Negative Regulation Of Protein Acetylation
Negative Regulation Of Transcription By RNA Polymerase II
Protein Modification Process
Histone Kinase Activity
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
DNA Damage Response
Protein Ubiquitination
Protection From Non-homologous End Joining At Telomere
Cellular Response To Reactive Oxygen Species
Positive Regulation Of DNA Replication
Positive Regulation Of Protein Ubiquitination
PML Body
Cyclin-dependent Protein Kinase Holoenzyme Complex
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Protein Modification By Small Protein Conjugation
Cellular Response To X-ray
Negative Regulation Of Protein Sumoylation
Male Germ Cell Nucleus
Positive Regulation Of Post-translational Protein Modification
Ubiquitin-dependent Protein Catabolic Process
Nucleoplasm
Epithelial Cell Differentiation
Modification-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Protein Binding
DNA Strand Resection Involved In Replication Fork Processing
Telomere Maintenance In Response To DNA Damage
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Tagcloud (Difference)
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Tagcloud (Intersection)
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