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TRIM37 and FAM124B
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
TRIM37
FAM124B
Gene Name
tripartite motif containing 37
family with sequence similarity 124B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Peroxisome
Cytosol
Aggresome
ESC/E(Z) Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Chromatin Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of NF-kappaB Transcription Factor Activity
Histone H2A Monoubiquitination
Histone H2A-K119 Monoubiquitination
Negative Regulation Of Centriole Replication
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Aggresome Assembly
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
59 interactors:
ANKRD11
APEX2
APTX
ARNT2
BYSL
CCDC33
CDC20B
CDK5RAP2
COPB1
CWF19L2
DDX6
DLGAP5
EWSR1
FAM107A
FAM124B
FAM161A
FAM50B
FXR2
KAT5
KIAA0408
KIF9
LTBR
MAGEB18
MCM10
MCRS1
NGFR
NUDT18
PBK
PNKP
PRC1
RASD1
RHPN1
RIBC2
RPL9
SCNM1
SSX2IP
TANK
TCEB3B
TNFRSF1B
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
UBASH3A
UBB
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2H
UBE2U
ZMAT2
ZNF329
ZNF417
ZNF655
29 interactors:
ADAMTSL4
AES
BIRC7
CARD9
CCDC85B
EFEMP2
GOLGA2
KCTD6
KCTD9
KIAA1958
KRT19
KRT31
KRT40
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP5-9
LZTS2
MDFI
MKRN3
NOTCH2NL
RBPMS
RINT1
SSX2IP
TCF4
TRIM37
TRIM54
TRIP6
USHBP1
Entrez ID
4591
79843
HPRD ID
05463
08663
Ensembl ID
ENSG00000108395
ENSG00000124019
Uniprot IDs
A8K0V9
A8K8U4
F8WEE6
O94972
Q9H5Z6
PDB IDs
3LRQ
Enriched GO Terms of Interacting Partners
?
Protein Polyubiquitination
TRIF-dependent Toll-like Receptor Signaling Pathway
Protein K48-linked Ubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Cellular Macromolecule Catabolic Process
Regulation Of Innate Immune Response
Protein K11-linked Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein K63-linked Ubiquitination
Cellular Response To Stress
Catabolic Process
Polynucleotide 3' Dephosphorylation
Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Protein Catabolic Process
Immune Response-regulating Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of DNA-templated Transcription In Response To Stress
Programmed Cell Death
I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Mitotic Cell Cycle Phase Transition
Cellular Response To DNA Damage Stimulus
Regulation Of Cell Cycle Phase Transition
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Proteolysis
Cell Death
Death
Activation Of NF-kappaB-inducing Kinase Activity
Modification-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Cellular Protein Catabolic Process
DNA Repair
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Proteolysis
Regulation Of Stress-activated MAPK Cascade
NIK/NF-kappaB Signaling
Regulation Of NIK/NF-kappaB Signaling
Regulation Of Metabolic Process
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Protein Localization To Nucleus
Regulation Of Nucleocytoplasmic Transport
Regulation Of Intracellular Transport
Regulation Of Binding
Regulation Of Intracellular Protein Transport
Negative Regulation Of Binding
Regulation Of Signal Transduction
Positive Regulation Of Nucleocytoplasmic Transport
Regulation Of Wnt Signaling Pathway
Positive Regulation Of JNK Cascade
Cellular Component Assembly
Regulation Of Signaling
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Cellular Localization
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Binding
Cell Differentiation Involved In Embryonic Placenta Development
Positive Regulation Of Intracellular Protein Transport
Regulation Of JNK Cascade
Activation Of JUN Kinase Activity
Regulation Of Protein Import Into Nucleus
Regulation Of Stress-activated MAPK Cascade
Regulation Of Protein Localization
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Natural Killer Cell Apoptotic Process
Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Binding
Positive Regulation Of Intracellular Transport
Negative Regulation Of Fat Cell Differentiation
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of JUN Kinase Activity
Wnt Signaling Pathway
Regulation Of Protein Transport
Negative Regulation Of Protein Localization To Nucleus
Regulation Of JUN Kinase Activity
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Histone H2A-K119 Monoubiquitination
JNK Cascade
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Establishment Of Protein Localization
Negative Regulation Of RNA Biosynthetic Process
Maintenance Of DNA Repeat Elements
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Tagcloud (Intersection)
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