STAC and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		STAC	FBXO25
Gene Name		SH3 and cysteine rich domain	F-box protein 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Metal Ion Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Signal Transduction Cellular Response To Heat Intracellular Signal Transduction	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Erectile dysfunction ( 22704111)
Protein-Protein Interactions		11 interactors: APP C9orf156 FBXO25 KANK2 KIAA1958 LIMD1 LMNA LZTS2 NCKIPSD NEDD4L TRIP6	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		6769	26260
HPRD ID		11890	16439
Ensembl ID		ENSG00000144681	ENSG00000147364
Uniprot IDs		E9PEA7 Q99469	Q8TCJ0
PDB IDs		2DL4
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Regulation Of Signaling Negative Regulation Of Signaling Regulation Of Protein Localization To Nucleus Nucleocytoplasmic Transport Nuclear Transport Regulation Of Protein Localization Sterol Regulatory Element Binding Protein Import Into Nucleus Regulation Of Cellular Localization Response To Abiotic Stimulus Cytoskeleton Organization Negative Regulation Of Vitamin D Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Protein Import Into Nucleus Nuclear Import Collateral Sprouting In Absence Of Injury Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Signal Transduction Positive Regulation Of Gene Silencing By MiRNA Negative Regulation Of Canonical Wnt Signaling Pathway Protein Import Release Of Cytoplasmic Sequestered NF-kappaB Collateral Sprouting Axon Midline Choice Point Recognition Protein Localization To Nucleus Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Hippo Signaling Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Caveolin-mediated Endocytosis Signaling Regulation Of Cellular Component Movement Cytoplasmic Transport Intracellular Transport Cell Communication Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Wnt Signaling Pathway Microtubule-based Process Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Tight Junction Assembly Regulation Of Hippo Signaling Positive Regulation Of Cell Aging Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Canonical Wnt Signaling Pathway Regulation Of Nucleic Acid-templated Transcription	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		17p 1p36 1q 1q13 1q21 4q21 7p 7q 8p 8q 8q11 9p aspscr1 cirrhotic etv1and ffpe fgfr3 gains hcc hccs maf nearby pathologically pter q23 q26 recql4 xp xq
Tagcloud (Difference) ?		17p 1p36 1q 1q13 1q21 4q21 7p 7q 8p 8q 8q11 9p aspscr1 cirrhotic etv1and ffpe fgfr3 gains hcc hccs maf nearby pathologically pter q23 q26 recql4 xp xq
Tagcloud (Intersection) ?