STAC and LZTS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		STAC	LZTS2
Gene Name		SH3 and cysteine rich domain	leucine zipper, putative tumor suppressor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cytoplasm Centrosome Microtubule Midbody
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Signal Transduction Cellular Response To Heat Intracellular Signal Transduction	Cytokinesis Kidney Development Mitotic Nuclear Division Negative Regulation Of Cell Proliferation Wnt Signaling Pathway Microtubule Severing Nuclear Export Spindle Midzone Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Erectile dysfunction ( 22704111)
Protein-Protein Interactions		11 interactors: APP C9orf156 FBXO25 KANK2 KIAA1958 LIMD1 LMNA LZTS2 NCKIPSD NEDD4L TRIP6	172 interactors: ABT1 AEN ANKRD11 ANKRD36BP1 AP1M1 ARHGAP32 ARMC7 ARNT2 ATPAF2 BAHD1 BEX2 BMS1P5 BYSL C14orf105 C19orf66 C1orf109 C20orf195 C6orf165 C8orf33 CARD9 CBX8 CCDC85B CCNC CCNG1 CCNK CDC23 CDK18 CDKL3 CEP57L1 CHCHD3 CLIP4 CNNM3 COPB1 CWF19L2 DCUN1D1 DGCR6 DGCR6L DYRK1A DYRK1B DYRK2 EHHADH EIF3D EIF4E2 FAM103A1 FAM107A FAM124B FAM161A FAM74A4 FANCL FBF1 FEM1C FGF12 FKBP6 FRG1 FRMD6 GCC1 GEM GFI1B GMCL1P1 GNL3L GPATCH2L GRB2 HLA-DPB1 HM13 HOMER2 HSPD1 IQCE KAT5 KAZN KIAA1683 KIF9 KIFC3 KPNA2 LASP1 LCK LIN37 LMO1 LMO2 MAB21L3 MAGEB4 MEMO1 MORF4L1 MORF4L2 MORN3 MOS MTA1 NCBP2 NCK2 NDE1 NEBL NEK6 NINL NIP7 OTUB2 PAK7 PITX1 PKP4 PLEKHN1 POLDIP3 POLR1C PPP1R18 PQBP1 PRKAB2 PSMA1 QARS RAC1 RAD51D RBFOX1 RBM15 RBM41 RBPMS RCOR3 RHNO1 RHOXF2 RIN1 RNF32 RNF41 RTP5 RUNX1T1 SCNM1 SH2D4A SH3RF2 SLC15A3 SLC25A6 SLU7 SMIM3 SNHG11 SNW1 SNX31 SPATA2 SPATA24 SPATC1L SPG7 SRSF2 STAC SUPV3L1 SUV39H1 TBC1D7 TCEA2 TCHP TEAD4 THAP10 THAP7 TNIP3 TRAF2 TRIM29 TRIM42 TSNAX TTC23 TXNL4A USF2 USP2 UTP14C WDYHV1 WT1-AS YTHDC1 ZBTB25 ZBTB38 ZGPAT ZKSCAN3 ZMAT1 ZMAT2 ZMYND19 ZNF20 ZNF250 ZNF417 ZNF426 ZNF446 ZNF490 ZNF512B ZNF572 ZNF581
Entrez ID		6769	84445
HPRD ID		11890	14341
Ensembl ID		ENSG00000144681	ENSG00000107816
Uniprot IDs		E9PEA7 Q99469	Q9BRK4
PDB IDs		2DL4
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Regulation Of Signaling Negative Regulation Of Signaling Regulation Of Protein Localization To Nucleus Nucleocytoplasmic Transport Nuclear Transport Regulation Of Protein Localization Sterol Regulatory Element Binding Protein Import Into Nucleus Regulation Of Cellular Localization Response To Abiotic Stimulus Cytoskeleton Organization Negative Regulation Of Vitamin D Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Protein Import Into Nucleus Nuclear Import Collateral Sprouting In Absence Of Injury Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Signal Transduction Positive Regulation Of Gene Silencing By MiRNA Negative Regulation Of Canonical Wnt Signaling Pathway Protein Import Release Of Cytoplasmic Sequestered NF-kappaB Collateral Sprouting Axon Midline Choice Point Recognition Protein Localization To Nucleus Regulation Of Vitamin D Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Hippo Signaling Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Caveolin-mediated Endocytosis Signaling Regulation Of Cellular Component Movement Cytoplasmic Transport Intracellular Transport Cell Communication Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Wnt Signaling Pathway Microtubule-based Process Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Tight Junction Assembly Regulation Of Hippo Signaling Positive Regulation Of Cell Aging Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Canonical Wnt Signaling Pathway Regulation Of Nucleic Acid-templated Transcription	RNA Metabolic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Viral Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Organelle Organization RNA Processing Ribonucleoprotein Complex Assembly Regulation Of Cellular Protein Metabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus RNA Splicing MRNA Processing Regulation Of Protein Metabolic Process Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome MRNA Metabolic Process RNA Splicing, Via Transesterification Reactions Positive Regulation Of Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Cell Cycle Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of T Cell Activation Cellular Process Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		17p 1p36 1q 1q13 1q21 4q21 7p 7q 8p 8q 8q11 9p aspscr1 cirrhotic etv1and ffpe fgfr3 gains hcc hccs maf nearby pathologically pter q23 q26 recql4 xp xq	a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1
Tagcloud (Difference) ?		17p 1p36 1q 1q13 1q21 4q21 7p 7q 8p 8q 8q11 9p aspscr1 cirrhotic etv1and ffpe fgfr3 gains hcc hccs maf nearby pathologically pter q23 q26 recql4 xp xq	a549 anticancer chemotherapeutic clones credits effectively exposing gltscr2 lats1 making mdr1 nf1 paclitaxel panel predetermined profiling pten regards screen screened shrna shrnas smad4 st14 suppressors tumorigenesis tumorigenic vhl wt1
Tagcloud (Intersection) ?