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AGTRAP and SPG21
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
AGTRAP
SPG21
Gene Name
angiotensin II receptor-associated protein
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Plasma Membrane
Cell Cortex
Integral Component Of Membrane
Cytoplasmic Vesicle Membrane
Intracellular Membrane-bounded Organelle
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Molecular Function
Angiotensin Type II Receptor Activity
Protein Binding
Protein Binding
CD4 Receptor Binding
Biological Process
Response To Hypoxia
Regulation Of Blood Pressure
Angiotensin-activated Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Systolic blood pressure (
19430483
)
Protein-Protein Interactions
70 interactors:
ACSF2
ADCK3
AGTR1
AGTR2
ALDH18A1
AP3M1
ARAF
ARFIP2
BPIFA2
C12orf10
CAPNS1
CD160
CPLX1
CRCT1
DDA1
DDX55
DGCR6
FAM114A1
FAM160A2
FAM64A
FARS2
FASTKD3
FATE1
GABARAPL2
GAD1
GAD2
GDNF
GNB2L1
GTF3C1
HARS2
HIST1H4G
HMGB1
HSCB
HSPA4
ISCU
KIAA0368
LMO2
LNX1
MCEE
MIEF1
MIEF2
MRM1
MTERF3
MUTYH
NDRG4
NFU1
NFYB
NKG7
PBX3
PCTP
PDHX
PITPNC1
PTPN9
RMDN2
SENP2
SNX1
SPG21
SSX3
SSX5
STAG3L1
SUCLA2
SYT16
TBRG4
TCEANC2
TFAM
TPD52L3
TUBA1B
TXN2
ZFYVE21
ZNF391
37 interactors:
AGTRAP
AKIRIN2
ARL6IP1
ATPAF2
CCDC102B
CCDC33
CD4
CMTM5
CRYAA
CTPS2
CUTC
DTX2
DTX3L
EFHC2
FAM114A1
GGA2
GSK3A
IKZF3
INCA1
KRT15
MID2
MTMR9
PRPS1
RABAC1
REEP6
RTN4
S100B
SPRED2
TCF12
TCF4
TFG
TRAF1
TRAF2
TRIM23
TRIM54
TRIM9
ZNF263
Entrez ID
57085
51324
HPRD ID
16379
10492
Ensembl ID
ENSG00000177674
ENSG00000090487
Uniprot IDs
Q6RW13
Q9NZD8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Succinate Metabolic Process
Glutamate Decarboxylation To Succinate
Glutamate Metabolic Process
Iron-sulfur Cluster Assembly
Renin-angiotensin Regulation Of Aldosterone Production
Regulation Of Blood Vessel Size By Renin-angiotensin
Dicarboxylic Acid Metabolic Process
Glutamate Catabolic Process
Angiotensin-activated Signaling Pathway
Positive Regulation Of Oxidoreductase Activity
Positive Regulation Of Protein Homooligomerization
Positive Regulation Of Mitochondrial Fission
Small Molecule Metabolic Process
Negative Regulation Of Phagocytosis
Regulation Of Mitochondrial Fission
Regulation Of Blood Volume By Renin-angiotensin
Dicarboxylic Acid Catabolic Process
Neurotransmitter Biosynthetic Process
Carboxylic Acid Metabolic Process
Regulation Of Oxidoreductase Activity
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Positive Regulation Of Protein Oligomerization
Regulation Of Renal Sodium Excretion
Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Carboxylic Acid Catabolic Process
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Organic Acid Metabolic Process
Positive Regulation Of Monooxygenase Activity
Regulation Of Excretion
Exploration Behavior
Regulation Of Protein Oligomerization
Neurotransmitter Metabolic Process
Neurotransmitter Secretion
Mitochondrion Organization
Ornithine Biosynthetic Process
Negative Regulation Of Apoptotic Cell Clearance
Succinyl-CoA Pathway
Posterior Compartment Specification
Anterior Compartment Pattern Formation
Aldosterone Secretion
Nitrogen Fixation
Vasodilation By Angiotensin Involved In Regulation Of Systemic Arterial Blood Pressure
L-methylmalonyl-CoA Metabolic Process
Phospholipase C-activating Angiotensin-activated Signaling Pathway
Positive Regulation Of Embryonic Development
Positive Regulation Of Protein Targeting To Membrane
Metanephros Morphogenesis
Cellular Amino Acid Catabolic Process
Cardiac Muscle Tissue Growth
Biosynthetic Process
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Protein Ubiquitination
Regulation Of Cell Death
Protein Modification By Small Protein Conjugation
Negative Regulation Of Developmental Growth
Innate Immune Response
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Striated Muscle Tissue Development
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Cell Death
Immune Response
Negative Regulation Of Organ Growth
Negative Regulation Of UDP-glucose Catabolic Process
Induction By Virus Of Host Cell-cell Fusion
Protein Palmitoleylation
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Striated Muscle Tissue Development
Regulation Of Cellular Localization
Negative Regulation Of Muscle Organ Development
Regulation Of Signal Transduction
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pyrimidine Nucleotide Biosynthetic Process
Regulation Of Intracellular Transport
Negative Regulation Of Cell Differentiation
Regulation Of Protein Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of SNARE Complex Assembly
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Urate Biosynthetic Process
'de Novo' CTP Biosynthetic Process
Glycogen Metabolic Process
Regulation Of Kinase Activity
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Differentiation
Positive Regulation Of Protein Binding
Regulation Of Skeletal Muscle Tissue Development
Regulation Of Cellular Ketone Metabolic Process
Gliogenesis
Negative Regulation Of Growth
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Tagcloud
?
adrenal
alpha1
apelin
apln
covers
ephx2
epoxide
genesis
gja1
glands
hydrolase
hypertensive
isolating
kynu
kynureninase
kyoto
normotensive
osteonectin
prone
rgs2
rising
shr
shrsp
sparc
spock2
substrains
urotensin
uts2
wky
Tagcloud (Difference)
?
adrenal
alpha1
apelin
apln
covers
ephx2
epoxide
genesis
gja1
glands
hydrolase
hypertensive
isolating
kynu
kynureninase
kyoto
normotensive
osteonectin
prone
rgs2
rising
shr
shrsp
sparc
spock2
substrains
urotensin
uts2
wky
Tagcloud (Intersection)
?