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AGTRAP and LNX1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
AGTRAP
LNX1
Gene Name
angiotensin II receptor-associated protein
ligand of numb-protein X 1, E3 ubiquitin protein ligase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Plasma Membrane
Cell Cortex
Integral Component Of Membrane
Cytoplasmic Vesicle Membrane
Intracellular Membrane-bounded Organelle
Cytoplasm
Molecular Function
Angiotensin Type II Receptor Activity
Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
PDZ Domain Binding
Biological Process
Response To Hypoxia
Regulation Of Blood Pressure
Angiotensin-activated Signaling Pathway
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS
Systolic blood pressure (
19430483
)
DNA methylation (variation) (
23725790
)
Protein-Protein Interactions
70 interactors:
ACSF2
ADCK3
AGTR1
AGTR2
ALDH18A1
AP3M1
ARAF
ARFIP2
BPIFA2
C12orf10
CAPNS1
CD160
CPLX1
CRCT1
DDA1
DDX55
DGCR6
FAM114A1
FAM160A2
FAM64A
FARS2
FASTKD3
FATE1
GABARAPL2
GAD1
GAD2
GDNF
GNB2L1
GTF3C1
HARS2
HIST1H4G
HMGB1
HSCB
HSPA4
ISCU
KIAA0368
LMO2
LNX1
MCEE
MIEF1
MIEF2
MRM1
MTERF3
MUTYH
NDRG4
NFU1
NFYB
NKG7
PBX3
PCTP
PDHX
PITPNC1
PTPN9
RMDN2
SENP2
SNX1
SPG21
SSX3
SSX5
STAG3L1
SUCLA2
SYT16
TBRG4
TCEANC2
TFAM
TPD52L3
TUBA1B
TXN2
ZFYVE21
ZNF391
218 interactors:
ABCA1
ABCB1
ABR
ACAT2
ACY3
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
APIP
APOL4
APP
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKC
BCR
BLVRA
BPIFA1
C1QTNF1
CA8
CALCOCO2
CAMK2N2
CATSPERD
CCDC101
CCDC102B
CCDC114
CCDC85B
CDA
CDC42EP4
CEP72
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK2
COIL
CPNE2
CTBP1
CTNND2
CTSO
CUTC
CXADR
DAB1
DAPK1
DCTD
DCUN1D5
DDX17
DEPTOR
DNPEP
DOCK9
DPF2
DVL3
EBF4
EHMT2
EIF4H
ENOX1
EPHB3
EXOC8
FAM118A
FAM124A
FAM212B
FAM9B
FBP1
FBXL12
FHL3
GAS2L2
GDI1
GIPR
GJD4
GOLPH3L
GPR142
GRB2
GRIN1
HMBOX1
HOMEZ
HSBP1
HTR2B
HUNK
IGSF5
IL3RA
ILF3
INSC
ISCU
JOSD1
KALRN
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KHDRBS3
KIAA1598
KLHL12
KRT15
KRTAP4-12
KRTAP4-2
KRTAP9-2
KXD1
LCLAT1
LDOC1
LGALS14
LGR6
LNX2
LRRC3B
LSM2
MAGEA11
MAGEB18
MAPK9
MEMO1
METTL21A
MRFAP1L1
MRPS24
MTMR9
MTUS2
MUSTN1
MVB12B
NADK
NAGK
NCK2
NECAB2
NEK6
NKD2
NME7
NOTCH2NL
NRCAM
NUDT14
NUMB
NUP37
NXT2
ORMDL3
OSBP2
OSGIN1
PAFAH1B3
PAICS
PBK
PBLD
PCBD1
PDZRN3
PDZRN4
PKDREJ
PKM
PKP4
POMGNT1
PPIA
PPID
PQBP1
PRR13
PTGIR
PTS
RABAC1
RAD51D
RAD54B
RBMX
RBMY1A1
RFPL3
ROBO3
ROPN1
RPIA
RUFY4
RUVBL2
SAPCD1
SAT1
SCLT1
SDK1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPF
SPHKAP
SRSF1
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
TBCEL
THAP7
TIFA
TMEM14C
TNFRSF18
TPM4
TRAF2
TRIM23
TRIM39
TRIM54
TRIP13
TRMT12
TSC2
TSC22D4
TSSK3
TYRO3
UBE2D2
ULK2
VCP
VRK2
WAC
WNT8A
WWP1
ZADH2
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZNF581
ZNF593
Entrez ID
57085
84708
HPRD ID
16379
17287
Ensembl ID
ENSG00000177674
ENSG00000072201
Uniprot IDs
Q6RW13
Q8TBB1
PDB IDs
3B76
Enriched GO Terms of Interacting Partners
?
Succinate Metabolic Process
Glutamate Decarboxylation To Succinate
Glutamate Metabolic Process
Iron-sulfur Cluster Assembly
Renin-angiotensin Regulation Of Aldosterone Production
Regulation Of Blood Vessel Size By Renin-angiotensin
Dicarboxylic Acid Metabolic Process
Glutamate Catabolic Process
Angiotensin-activated Signaling Pathway
Positive Regulation Of Oxidoreductase Activity
Positive Regulation Of Protein Homooligomerization
Positive Regulation Of Mitochondrial Fission
Small Molecule Metabolic Process
Negative Regulation Of Phagocytosis
Regulation Of Mitochondrial Fission
Regulation Of Blood Volume By Renin-angiotensin
Dicarboxylic Acid Catabolic Process
Neurotransmitter Biosynthetic Process
Carboxylic Acid Metabolic Process
Regulation Of Oxidoreductase Activity
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Positive Regulation Of Protein Oligomerization
Regulation Of Renal Sodium Excretion
Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Carboxylic Acid Catabolic Process
Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin
Organic Acid Metabolic Process
Positive Regulation Of Monooxygenase Activity
Regulation Of Excretion
Exploration Behavior
Regulation Of Protein Oligomerization
Neurotransmitter Metabolic Process
Neurotransmitter Secretion
Mitochondrion Organization
Ornithine Biosynthetic Process
Negative Regulation Of Apoptotic Cell Clearance
Succinyl-CoA Pathway
Posterior Compartment Specification
Anterior Compartment Pattern Formation
Aldosterone Secretion
Nitrogen Fixation
Vasodilation By Angiotensin Involved In Regulation Of Systemic Arterial Blood Pressure
L-methylmalonyl-CoA Metabolic Process
Phospholipase C-activating Angiotensin-activated Signaling Pathway
Positive Regulation Of Embryonic Development
Positive Regulation Of Protein Targeting To Membrane
Metanephros Morphogenesis
Cellular Amino Acid Catabolic Process
Cardiac Muscle Tissue Growth
Biosynthetic Process
Cellular Component Assembly
Protein Homooligomerization
Protein Oligomerization
Protein Complex Assembly
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Cellular Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Regulation Of Cellular Component Organization
Cellular Aromatic Compound Metabolic Process
Regulation Of Rho Protein Signal Transduction
Response To Stimulus
Developmental Process
Cellular Metabolic Process
Peptidyl-lysine Dimethylation
Heterocycle Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Neutrophil Degranulation
Cellular Response To Stimulus
Viral Process
Programmed Cell Death
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Nitrogen Compound Metabolic Process
Protein Tetramerization
Cell Death
Apoptotic Process
Death
Neuron Recognition
Cell Communication
Signaling
Regulation Of Neutrophil Degranulation
Negative Regulation Of Neutrophil Activation
Viral Release From Host Cell
Regulation Of Rho GTPase Activity
Cell-cell Junction Organization
Protein Autophosphorylation
Response To Abiotic Stimulus
Organelle Organization
Regulation Of Cell Morphogenesis
Nitrogen Compound Metabolic Process
Axon Midline Choice Point Recognition
Positive Regulation Of Rho GTPase Activity
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Homodimerization Activity
Regulation Of Ras Protein Signal Transduction
Protein Heterooligomerization
Biosynthetic Process
Tagcloud
?
adrenal
alpha1
apelin
apln
covers
ephx2
epoxide
genesis
gja1
glands
hydrolase
hypertensive
isolating
kynu
kynureninase
kyoto
normotensive
osteonectin
prone
rgs2
rising
shr
shrsp
sparc
spock2
substrains
urotensin
uts2
wky
Tagcloud (Difference)
?
adrenal
alpha1
apelin
apln
covers
ephx2
epoxide
genesis
gja1
glands
hydrolase
hypertensive
isolating
kynu
kynureninase
kyoto
normotensive
osteonectin
prone
rgs2
rising
shr
shrsp
sparc
spock2
substrains
urotensin
uts2
wky
Tagcloud (Intersection)
?