AGTRAP and ATP5F1E

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AGTRAP	ATP5F1E
Description		angiotensin II receptor associated protein	ATP synthase F1 subunit epsilon
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Cortex Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Proton-transporting ATP Synthase Complex
	Molecular Function	Angiotensin Type II Receptor Activity Protein Binding Identical Protein Binding	Protein Binding Hydrolase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Signaling by BRAF and RAF1 fusions	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Basophil percentage of white cells ( 32888494) Systolic blood pressure ( 19430483)
Interacting Genes		138 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 ANKS6 AP3M1 APOA4 AQP6 ARAF ARFIP2 ARHGAP1 ATP5F1E BCL2L13 BPIFA2 CAPNS1 CCDC70 CD160 CD79A CELA3A CIAO2A COQ8A CPLX1 CPLX4 CRCT1 CYB5R3 CYBC1 DDA1 DDX55 DGCR6 DIABLO DNAJC1 ECPAS ERGIC3 ETFRF1 FAM114A1 FAM209A FARS2 FASTKD3 FATE1 FFAR2 FGA FHIP1B FNDC9 GABARAPL2 GAD1 GAD2 GDNF GPR152 GPX8 GTF2H1 GTF3C1 H4C7 HARS2 HIBADH HMGB1 HSBP1L1 HSCB HSD17B13 HSFX1 HSFX2 HSPA4 IL7R ISCU KCNK5 KIR2DL3 KIR3DL3 LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MGST3 MIEF1 MIEF2 MMD MRM1 MRPL11 MRRF MTERF3 MUTYH MYG1 NDRG4 NDUFAF3 NFU1 NFYB NKG7 PBX3 PCTP PCYT1A PDHX PIMREG PITPNC1 PNPO POLDIP2 PPIF PRPF18 PTPN9 RAB30 RACK1 RBFA RETREG3 RMDN2 S100B SCAND1 SENP2 SH3GLB1 SLC18A1 SLC7A14 SMG9 SNX1 SPG21 SSX3 SSX5 STAG3L1 STAR STARD4 STMN4 STX1A SUCLA2 SYT16 TBRG4 TCEA2 TCEANC2 TFAM THAP4 TMEM139 TMEM14B TMEM31 TMPPE TPD52L3 TTPA TUBA1B TXN2 UBE2I YARS2 ZFYVE21 ZNF391	2 interacting genes: AGTRAP CYP17A1
Entrez ID		57085	514
HPRD ID		16379	05856
Ensembl ID		ENSG00000177674	ENSG00000124172
Uniprot IDs		Q6RW13	P56381
PDB IDs			8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Mitochondrial Matrix Mitochondrion Protein Binding Lipid Binding Succinate Metabolic Process Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity	Cortisol Biosynthetic Process Androgen Biosynthetic Process Steroid 17-alpha-monooxygenase Activity Glucocorticoid Biosynthetic Process Cortisol Metabolic Process Angiotensin Type II Receptor Activity Progesterone Metabolic Process Steroid Hydroxylase Activity Glucocorticoid Metabolic Process Sex Differentiation C21-steroid Hormone Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Androgen Metabolic Process Steroid Hormone Biosynthetic Process Angiotensin-activated Signaling Pathway Endoplasmic Reticulum Membrane Ketone Biosynthetic Process Hormone Biosynthetic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Monooxygenase Activity Endoplasmic Reticulum Steroid Biosynthetic Process Ketone Metabolic Process Iron Ion Binding Heme Binding Olefinic Compound Metabolic Process Lyase Activity Regulation Of Blood Pressure Cytoplasmic Vesicle Membrane Cell Cortex Hormone Metabolic Process Regulation Of Biological Quality
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