GRIPAP1 and SPP1

Number of citations of the paper that reports this interaction (PMID 22779921)
1

Data Source:
BioGRID (two hybrid)

		GRIPAP1	SPP1
Gene Name		GRIP1 associated protein 1	secreted phosphoprotein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Blood Microparticle	Extracellular Region Extracellular Space Cell Projection Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Molecular_function	Cytokine Activity Protein Binding Extracellular Matrix Binding
	Biological Process	Biological_process	Osteoblast Differentiation Inflammatory Response Cell Adhesion Embryo Implantation Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Neutrophil Chemotaxis Biomineral Tissue Development Response To Vitamin D Positive Regulation Of Bone Resorption Decidualization Response To Steroid Hormone Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Pathways			Signaling by PDGF Integrin cell surface interactions Degradation of the extracellular matrix
Drugs
Diseases
GWAS			Dental caries ( 23064961)
Protein-Protein Interactions		12 interactors: ARL15 CASP3 CCNT1 GRIA1 GRIP1 GRM7 RAB4A SMAD2 SMURF1 SPP1 TCEA2 TES	88 interactors: ABCF3 ACP5 AFF4 AMOTL2 APOA1 ATP2A2 ATP5F1 BAG6 BRD3 C1RL C2orf50 CACNG4 CALM1 CC2D1B CD44 CEP162 CHD1 CISD2 CMTM3 COMMD1 COPS5 CSNK2A1 CSNK2A2 CTNNBL1 CYB5R3 DCX DNAJB1 DNTTIP2 DSEL EEF1A1 EIF3K EPAS1 F2 FTH1 GRIPAP1 HBA2 HMGN1 IGFBP5 ITGA5 ITGA9 ITGAV ITGB1 KCNIP1 LRRC4 MAP1A MAP1B MARCKS MEOX2 MMP3 MMP7 MPPED1 MRPL23 NACA NCKAP1 NCSTN PDLIM7 PEMT PEPD PLD3 PRKACB PRKCA PRKG1 RANBP9 RAPGEF2 RBBP6 RIMS4 RPL13 RPL15 RPL5 RPS13 SEC24C SGTA SLC39A6 SNAPIN SSB STAU1 STK39 TBC1D8 TMEM168 TMEM30A TPT1 TTC1 TUBB UBQLN4 USP42 USP8 ZNF638 ZNF804A
Entrez ID		56850	6696
HPRD ID		02325	01325
Ensembl ID		ENSG00000068400	ENSG00000118785
Uniprot IDs		Q4V328	B7Z351 P10451 Q3LGB0
PDB IDs			3CXD 3DSF
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Stimulus Response To Transforming Growth Factor Beta Signal Transduction Cellular Response To Growth Factor Stimulus Response To Growth Factor Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Signaling Regulation Of Cellular Process Cell Communication Glutamate Receptor Signaling Pathway Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Stimulus Enzyme Linked Receptor Protein Signaling Pathway Receptor Metabolic Process Regulation Of BMP Signaling Pathway Cell-cell Signaling DNA-templated Transcription, Elongation Extracellular Matrix Disassembly Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Intracellular Signal Transduction Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Protein Localization Memory Cell Surface Receptor Signaling Pathway Sensory Perception Of Sound Synaptic Transmission Positive Regulation Of Mesoderm Development Conditioned Taste Aversion Primary MiRNA Processing Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Ubiquitin-dependent SMAD Protein Catabolic Process Regulation Of Nodal Signaling Pathway Negative Regulation Of Collateral Sprouting Negative Regulation Of Glutamate Secretion Common-partner SMAD Protein Phosphorylation Glial Cell Apoptotic Process Sensory Perception Of Mechanical Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Apoptotic DNA Fragmentation	Wound Healing Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Neuron Projection Development Response To Wounding Chemotaxis Locomotion Membrane Organization Cell Projection Organization Axon Development Neuron Development Developmental Process Regulation Of Body Fluid Levels Cellular Localization Extracellular Matrix Organization Regulation Of Proteasomal Protein Catabolic Process Extracellular Structure Organization Chemical Homeostasis Anatomical Structure Development Axon Guidance Axonogenesis System Development Leukocyte Migration Translational Initiation Viral Process Ion Homeostasis Regulation Of Cellular Process Nervous System Development Multicellular Organismal Development Cell Migration Neuron Differentiation Metal Ion Homeostasis Cell Morphogenesis Involved In Neuron Differentiation Translational Elongation Immune System Process Integrin-mediated Signaling Pathway Viral Life Cycle Anatomical Structure Morphogenesis Cell Motility Homeostatic Process Neuron Projection Morphogenesis Heterotypic Cell-cell Adhesion Response To Stress Generation Of Neurons Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cell Development Regulation Of Protein Metabolic Process
Tagcloud ?			able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose
Tagcloud (Difference) ?			able acquisition acts carcinomas cbx7 chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive suppose take transcriptional whose
Tagcloud (Intersection) ?