GRIPAP1 and DUSP26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GRIPAP1	DUSP26
Description		GRIP1 associated protein 1	dual specificity phosphatase 26
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Cytosol Membrane Axon Dendrite Early Endosome Membrane Presynaptic Membrane Cell Projection Neuronal Cell Body Synapse Recycling Endosome Membrane Blood Microparticle Glutamatergic Synapse Extrinsic Component Of Postsynaptic Early Endosome Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding	P53 Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Phosphatase Activity MAP Kinase Phosphatase Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Protein Transport Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Negative Regulation Of Protein Localization Negative Regulation Of Receptor Clustering	Negative Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Negative Regulation Of MAPK Cascade Positive Regulation Of Cell Adhesion Negative Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494)	Body mass index ( 25673413 28892062) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Metabolite levels ( 23823483) Morning person ( 30696823) Reading disability ( 32108986) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		70 interacting genes: AARD ANKRD11 ARL15 ATG5 BYSL CASP3 CBX8 CCDC185 CCDC187 CCNH CCNT1 CDC37 CEP57L1 CFAP53 CWF19L2 DAXX DISC1 DNAAF19 DRC4 DUSP26 EHHADH ELOA ENKD1 FAM161A FAM50B FAM90A1 FXR1 GRIA1 GRIP1 GRM7 HDAC4 HSPB1 ING4 ING5 LNX1 MAP3K1 MEOX2 MFAP1 MLLT6 NUAK2 PIBF1 PKP2 PPP1R18 PRPF18 PSMB1 RAB4A RCOR3 SMAD2 SMARCE1 SMURF1 SNAPC5 SNW1 SPP1 STAP1 TBC1D30 TCEA2 TEPSIN TES TRAF2 TSGA10IP TSHZ2 TSNAX TTC23 UBC USP2 ZMAT2 ZNF219 ZNF250 ZNF35 ZNF835	11 interacting genes: CALCOCO2 CARD10 EPHA2 EPHA7 GOLGA6L9 GRIPAP1 HSF4 IGF1R KRT27 PTK7 RET
Entrez ID		56850	78986
HPRD ID		02325	14421
Ensembl ID		ENSG00000068400	ENSG00000133878
Uniprot IDs		Q4V328	Q9BV47
PDB IDs			2E0T 4B04 4HRF 5GTJ
Enriched GO Terms of Interacting Partners?		Nucleoplasm Protein Binding DNA Replication-dependent Chromatin Disassembly	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Tissue Morphogenesis Protein Kinase Activity Axon Guidance Receptor Activity Ephrin Receptor Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Axon Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Receptor Complex Positive Regulation Of Protein-containing Complex Disassembly Neuron Projection Guidance Axon Guidance Growth Factor Binding Positive Regulation Of Cellular Component Organization Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Plasma Membrane Bounded Cell Projection Organization Notochord Cell Development Kinase Activity Ephrin Receptor Signaling Pathway Regulation Of MAPK Cascade Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Cell Projection Organization Extrinsic Component Of Postsynaptic Early Endosome Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Retinoic Acid ATP Binding Anatomical Structure Morphogenesis Axial Mesoderm Formation Neuronal Cell Body Posterior Midgut Development Negative Regulation Of Receptor Clustering Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Negative Regulation Of Lymphangiogenesis Notochord Formation Plasma Membrane Bounded Cell Projection Organization Insulin-like Growth Factor Receptor Activity Protein Kinase Complex Insulin Receptor Activity Response To Retinoic Acid Peyer's Patch Morphogenesis Positive Regulation Of Metanephric Glomerulus Development Regulation Of Cellular Component Organization Regulation Of Neuron Projection Development Regulation Of Protein Localization To Plasma Membrane Regulation Of Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Insulin Receptor Complex
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