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GRIPAP1 and GRIA1
Number of citations of the paper that reports this interaction (PMID
10896157
)
23
Data Source:
HPRD
(in vivo)
GRIPAP1
GRIA1
Gene Name
GRIP1 associated protein 1
glutamate receptor, ionotropic, AMPA 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Early Endosome
Blood Microparticle
Endoplasmic Reticulum Membrane
Plasma Membrane
Synaptic Vesicle
Cell Surface
Postsynaptic Density
Cell Junction
Dendrite
Endocytic Vesicle Membrane
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex
Dendrite Membrane
Dendritic Spine Membrane
Neuronal Cell Body
Dendritic Spine
Axonal Spine
Neuron Spine
Postsynaptic Membrane
Recycling Endosome
Molecular Function
Molecular_function
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Protein Binding
Glutamate Receptor Activity
PDZ Domain Binding
Biological Process
Biological_process
Signal Transduction
Synaptic Transmission
Long-term Memory
Receptor Internalization
Ion Transmembrane Transport
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Long Term Synaptic Depression
Pathways
Trafficking of GluR2-containing AMPA receptors
Activation of NMDA receptor upon glutamate binding and postsynaptic events
Activation of AMPA receptors
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Trafficking of AMPA receptors
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Unblocking of NMDA receptor, glutamate binding and activation
Transmission across Chemical Synapses
Drugs
L-Glutamic Acid
Enflurane
Isoflurane
Methoxyflurane
Desflurane
Sevoflurane
Perampanel
Diseases
GWAS
Aging (time to event) (
21782286
)
Anthropometric traits (
19260139
)
Asparaginase hypersensitivity in acute lymphoblastic leukemia (
20592726
)
Obesity-related traits (
23251661
)
Sudden cardiac arrest (
21658281
)
Protein-Protein Interactions
12 interactors:
ARL15
CASP3
CCNT1
GRIA1
GRIP1
GRM7
RAB4A
SMAD2
SMURF1
SPP1
TCEA2
TES
22 interactors:
CACNG2
CAMK2G
CANX
CASP8
CXCR2
DLG1
EPB41L1
EPB41L2
GRIA4
GRID2
GRIK2
GRIP1
GRIPAP1
HOMER1
HSPA5
PICK1
PRKACA
PRKCA
SDCBP
SQSTM1
TANC1
TRPC1
Entrez ID
56850
2890
HPRD ID
02325
00695
Ensembl ID
ENSG00000068400
ENSG00000155511
Uniprot IDs
Q4V328
P42261
Q59GL5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
Cellular Response To Stimulus
Response To Transforming Growth Factor Beta
Signal Transduction
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Signaling
Regulation Of Cellular Process
Cell Communication
Glutamate Receptor Signaling Pathway
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Receptor Metabolic Process
Regulation Of BMP Signaling Pathway
Cell-cell Signaling
DNA-templated Transcription, Elongation
Extracellular Matrix Disassembly
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Intracellular Signal Transduction
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Zygotic Specification Of Dorsal/ventral Axis
Protein Localization
Memory
Cell Surface Receptor Signaling Pathway
Sensory Perception Of Sound
Synaptic Transmission
Positive Regulation Of Mesoderm Development
Conditioned Taste Aversion
Primary MiRNA Processing
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Ubiquitin-dependent SMAD Protein Catabolic Process
Regulation Of Nodal Signaling Pathway
Negative Regulation Of Collateral Sprouting
Negative Regulation Of Glutamate Secretion
Common-partner SMAD Protein Phosphorylation
Glial Cell Apoptotic Process
Sensory Perception Of Mechanical Stimulus
Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Activin Receptor Signaling Pathway
Regulation Of Apoptotic DNA Fragmentation
Synaptic Transmission
Cell-cell Signaling
Signaling
Cell Communication
Response To External Stimulus
Positive Regulation Of Macrophage Differentiation
Glutamate Receptor Signaling Pathway
Protein Localization
Cortical Actin Cytoskeleton Organization
Positive Regulation Of Dense Core Granule Biogenesis
Developmental Process
Cortical Cytoskeleton Organization
Cell Differentiation
Nervous System Development
Histone H3-T6 Phosphorylation
Positive Regulation Of Transport
Cell Surface Receptor Signaling Pathway
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Negative Regulation Of Programmed Cell Death
Neutrophil Chemotaxis
Chemotaxis
Anatomical Structure Development
Apoptotic Signaling Pathway
Receptor Clustering
System Development
Neutrophil Migration
Positive Regulation Of Myeloid Leukocyte Differentiation
Regulation Of Ion Transport
Negative Regulation Of Cell Death
Granulocyte Chemotaxis
Peptidyl-serine Autophosphorylation
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Anatomical Structure Morphogenesis
Intrinsic Apoptotic Signaling Pathway
Cell Activation
Regulation Of Cellular Localization
Regulation Of Apoptotic Process
Regulation Of Calcium Ion Transport
Cellular Metal Ion Homeostasis
Neuron-neuron Synaptic Transmission
Regulation Of Signaling
Signal Transduction
Dendritic Spine Maintenance
Response To Cytokine
Desmosome Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Cell Death
Tagcloud
?
acutely
arc
camksmall
cyrillicalpha
dioxide
durations
environ
gria2
grin1
grin2a
grin2b
implied
inc
inhalation
inhaled
lifelong
m3
periodicals
pka
pollutant
postsynaptic
presynaptic
psd
so2
synapse
synaptophysin
toxicol
ubiquitous
wiley
Tagcloud (Difference)
?
acutely
arc
camksmall
cyrillicalpha
dioxide
durations
environ
gria2
grin1
grin2a
grin2b
implied
inc
inhalation
inhaled
lifelong
m3
periodicals
pka
pollutant
postsynaptic
presynaptic
psd
so2
synapse
synaptophysin
toxicol
ubiquitous
wiley
Tagcloud (Intersection)
?