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GRIPAP1 and GRM7
Number of citations of the paper that reports this interaction (PMID
11891216
)
25
Data Source:
HPRD
(two hybrid, in vitro)
GRIPAP1
GRM7
Gene Name
GRIP1 associated protein 1
glutamate receptor, metabotropic 7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Early Endosome
Blood Microparticle
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Cortex
Integral Component Of Membrane
Axon
Dendrite
Asymmetric Synapse
Presynaptic Membrane
Dendritic Shaft
Receptor Complex
Postsynaptic Membrane
Presynaptic Active Zone
Molecular Function
Molecular_function
Group III Metabotropic Glutamate Receptor Activity
Voltage-gated Calcium Channel Activity
Calcium Channel Regulator Activity
Calcium Ion Binding
Glutamate Receptor Activity
Adenylate Cyclase Inhibitor Activity
Glutamate Binding
PDZ Domain Binding
Serine Binding
Biological Process
Biological_process
Conditioned Taste Aversion
Behavioral Fear Response
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G-protein Coupled Glutamate Receptor Signaling Pathway
Synaptic Transmission
Sensory Perception Of Sound
Sensory Perception Of Smell
Short-term Memory
Negative Regulation Of Glutamate Secretion
Transmission Of Nerve Impulse
Adult Behavior
Negative Regulation Of CAMP Biosynthetic Process
Regulation Of Cyclase Activity
Regulation Of Synaptic Transmission, Glutamatergic
Calcium Ion Transmembrane Transport
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
L-Glutamic Acid
Diseases
GWAS
Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors) (
23648065
)
Major depressive disorder (broad) (
20038947
)
Orofacial clefts (
22419666
)
Panic disorder (
19165232
)
Personality dimensions (
21368711
)
Visceral adipose tissue adjusted for BMI (
22589738
)
Protein-Protein Interactions
12 interactors:
ARL15
CASP3
CCNT1
GRIA1
GRIP1
GRM7
RAB4A
SMAD2
SMURF1
SPP1
TCEA2
TES
12 interactors:
CALM1
CALM2
CALM3
FLNA
GNAQ
GRIPAP1
PICK1
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
Entrez ID
56850
2917
HPRD ID
02325
04979
Ensembl ID
ENSG00000068400
ENSG00000196277
Uniprot IDs
Q4V328
B2R693
B9EGG9
Q14831
Q59G95
PDB IDs
3MQ4
Enriched GO Terms of Interacting Partners
?
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
Cellular Response To Stimulus
Response To Transforming Growth Factor Beta
Signal Transduction
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Signaling
Regulation Of Cellular Process
Cell Communication
Glutamate Receptor Signaling Pathway
Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Response To Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Receptor Metabolic Process
Regulation Of BMP Signaling Pathway
Cell-cell Signaling
DNA-templated Transcription, Elongation
Extracellular Matrix Disassembly
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Intracellular Signal Transduction
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Zygotic Specification Of Dorsal/ventral Axis
Protein Localization
Memory
Cell Surface Receptor Signaling Pathway
Sensory Perception Of Sound
Synaptic Transmission
Positive Regulation Of Mesoderm Development
Conditioned Taste Aversion
Primary MiRNA Processing
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Ubiquitin-dependent SMAD Protein Catabolic Process
Regulation Of Nodal Signaling Pathway
Negative Regulation Of Collateral Sprouting
Negative Regulation Of Glutamate Secretion
Common-partner SMAD Protein Phosphorylation
Glial Cell Apoptotic Process
Sensory Perception Of Mechanical Stimulus
Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Activin Receptor Signaling Pathway
Regulation Of Apoptotic DNA Fragmentation
Platelet Degranulation
Platelet Activation
Protein Polymerization
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Regulation Of High Voltage-gated Calcium Channel Activity
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Activation Of Phospholipase C Activity
'de Novo' Posttranslational Protein Folding
Positive Regulation Of Phospholipase C Activity
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
'de Novo' Protein Folding
Blood Coagulation
Hemostasis
Detection Of Calcium Ion
Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Phosphoprotein Phosphatase Activity
Positive Regulation Of Phospholipase Activity
Positive Regulation Of Peptidyl-threonine Phosphorylation
Positive Regulation Of Protein Autophosphorylation
Regulation Of Phospholipase Activity
Positive Regulation Of Nitric-oxide Synthase Activity
Positive Regulation Of Lipase Activity
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Glycogen Catabolic Process
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Voltage-gated Calcium Channel Activity
Positive Regulation Of Protein Dephosphorylation
Negative Regulation Of Cation Channel Activity
Regulation Of Body Fluid Levels
Polysaccharide Catabolic Process
Positive Regulation Of Monooxygenase Activity
Wound Healing
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Positive Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Rhodopsin Mediated Signaling Pathway
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Activation Of Adenylate Cyclase Activity
Nitric Oxide Metabolic Process
Cellular Protein Complex Assembly
Exocytosis
Cell Activation
Regulation Of Protein Autophosphorylation
Reactive Nitrogen Species Metabolic Process
Rhodopsin Mediated Signaling Pathway
Cellular Carbohydrate Catabolic Process
Response To Wounding
Positive Regulation Of Phosphatase Activity
Tagcloud
?
adhd
asparate
biased
cdi
chi2
cpt
deficit
disequilibrium
ga
genotype
gg
grin2a
grin2b
hyperactivity
inventory
ionotropic
korean
metabotropic
mglur7
omission
preferential
probands
rs2284411
rs3792452
rs37952452
rs8049651
staic
tdt
trios
Tagcloud (Difference)
?
adhd
asparate
biased
cdi
chi2
cpt
deficit
disequilibrium
ga
genotype
gg
grin2a
grin2b
hyperactivity
inventory
ionotropic
korean
metabotropic
mglur7
omission
preferential
probands
rs2284411
rs3792452
rs37952452
rs8049651
staic
tdt
trios
Tagcloud (Intersection)
?