GRIPAP1 and PPP1R18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GRIPAP1	PPP1R18
Description		GRIP1 associated protein 1	protein phosphatase 1 regulatory subunit 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endosome Cytosol Membrane Axon Dendrite Early Endosome Membrane Presynaptic Membrane Cell Projection Neuronal Cell Body Synapse Recycling Endosome Membrane Blood Microparticle Glutamatergic Synapse Extrinsic Component Of Postsynaptic Early Endosome Membrane	Cytoplasm Cytoskeleton
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Protein Transport Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Negative Regulation Of Protein Localization Negative Regulation Of Receptor Clustering
Pathways
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494)	Autism spectrum disorder or schizophrenia ( 28540026) Chronic obstructive pulmonary disease ( 33909500) Hemoglobin levels ( 32327693) Lung cancer ( 28604730)
Interacting Genes		70 interacting genes: AARD ANKRD11 ARL15 ATG5 BYSL CASP3 CBX8 CCDC185 CCDC187 CCNH CCNT1 CDC37 CEP57L1 CFAP53 CWF19L2 DAXX DISC1 DNAAF19 DRC4 DUSP26 EHHADH ELOA ENKD1 FAM161A FAM50B FAM90A1 FXR1 GRIA1 GRIP1 GRM7 HDAC4 HSPB1 ING4 ING5 LNX1 MAP3K1 MEOX2 MFAP1 MLLT6 NUAK2 PIBF1 PKP2 PPP1R18 PRPF18 PSMB1 RAB4A RCOR3 SMAD2 SMARCE1 SMURF1 SNAPC5 SNW1 SPP1 STAP1 TBC1D30 TCEA2 TEPSIN TES TRAF2 TSGA10IP TSHZ2 TSNAX TTC23 UBC USP2 ZMAT2 ZNF219 ZNF250 ZNF35 ZNF835	80 interacting genes: ABRA ACTN3 BICD2 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC88B CDR2L CEP70 COG6 DES DZIP1 EIF3L FAM9B FHL5 FSD2 GCC1 GFAP GMCL1 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GTPBP3 HAP1 HOMER3 HOOK2 HSF2BP IKZF3 KASH5 KCTD9 KRT13 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT36 KRT40 LDOC1 LZTS1 LZTS2 MAD1L1 MAPK1 MEOX2 MID2 MRPL38 MTUS2 NACA NEFL PDE4DIP PIBF1 PLEKHF2 PPP1CA PPP1CC PPP1R13B PRPH SORBS3 SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM62 TRIM69 TSC1 TSGA10 VIM VPS52 ZMYND12 ZRANB1
Entrez ID		56850	170954
HPRD ID		02325	11172
Ensembl ID		ENSG00000068400	ENSG00000146112
Uniprot IDs		Q4V328	A0A024RCJ8 A0A0G2JHC2 Q6NYC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Protein Binding DNA Replication-dependent Chromatin Disassembly	Cytoskeleton Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Intermediate Filament Organelle Organization Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Keratin Filament Structural Constituent Of Cytoskeleton Structural Molecule Activity Protein Binding Identical Protein Binding Intermediate Filament Cytoskeleton Microtubule-based Process Centrosome Morphogenesis Of An Epithelium Microtubule Cytoskeleton Organization Tissue Morphogenesis Cytosol Cytoplasm Microtubule Organizing Center Bergmann Glial Cell Differentiation Epithelial Cell Differentiation Microtubule Organizing Center Organization Negative Regulation Of Viral Transcription Intracellular Transport Developmental Process Regulation Of Viral Transcription Response To Muramyl Dipeptide Cellular Developmental Process Positive Regulation Of Skeletal Muscle Tissue Growth Establishment Of Localization In Cell Developmental Process Involved In Reproduction Establishment Of Protein Localization Dynein Light Intermediate Chain Binding Cytoskeleton-dependent Intracellular Transport Kinetochore Binding Regulation Of Autophagy Cell Differentiation Regulation Of Skeletal Muscle Tissue Growth Z Disc Intracellular Protein Localization Protein Transport Astrocyte Differentiation PTW/PP1 Phosphatase Complex Cellular Localization Organelle Transport Along Microtubule Cellular Response To Muramyl Dipeptide
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