ING3 and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		ING3	FBXO25
Gene Name		inhibitor of growth family, member 3	F-box protein 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Histone Acetyltransferase Activity Zinc Ion Binding Methylated Histone Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Growth Positive Regulation Of Apoptotic Process Histone H4 Acetylation Histone H2A Acetylation	Protein Ubiquitination
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP FBXO25 NR1H2 NR1H3 TEX11 TRIM54 USHBP1	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		54556	26260
HPRD ID		06321	16439
Ensembl ID		ENSG00000071243	ENSG00000147364
Uniprot IDs		Q9NXR8	Q8TCJ0
PDB IDs		1X4I
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Pinocytosis Negative Regulation Of Cholesterol Storage Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Cholesterol Homeostasis Positive Regulation Of Cholesterol Efflux Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Cholesterol Transport Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage Regulation Of Cholesterol Efflux Regulation Of Triglyceride Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Negative Regulation Of Lipid Transport Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Cholesterol Transport Regulation Of Triglyceride Metabolic Process Negative Regulation Of Innate Immune Response Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Endocytosis Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Lipid Storage Positive Regulation Of Lipid Transport Regulation Of Protein Processing Positive Regulation Of Lipid Biosynthetic Process Cholesterol Homeostasis Sterol Homeostasis Regulation Of Cellular Ketone Metabolic Process Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Lipase Activity Regulation Of Lipid Transport Steroid Hormone Mediated Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Secretion Of Lysosomal Enzymes Negative Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Lipid Homeostasis Regulation Of Proteolysis Negative Regulation Of Immune Response Hormone-mediated Signaling Pathway Regulation Of Lipid Biosynthetic Process Synaptic Growth At Neuromuscular Junction	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		adenocarcinoma adenoma carcinogenesis clinicopathological colo201 colo205 colorectal depth dld downregulated forming hct ht immunohistochemically interpretation invasion kaplan km lymphatic meier mucosa neoplastic nnm node staging sw480 sw620 venous widr
Tagcloud (Difference) ?		adenocarcinoma adenoma carcinogenesis clinicopathological colo201 colo205 colorectal depth dld downregulated forming hct ht immunohistochemically interpretation invasion kaplan km lymphatic meier mucosa neoplastic nnm node staging sw480 sw620 venous widr
Tagcloud (Intersection) ?