ING3

Description		inhibitor of growth family member 3
Image
GO Annotations	Cellular Component	Nucleosome Swr1 Complex Nucleus Nucleoplasm Piccolo Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Zinc Ion Binding Histone H4 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Histone H2A Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity Histone H3K4me3 Reader Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: FOXP2
Interacting Genes		9 interacting genes: APP BEX5 FBXO25 NR1H2 NR1H3 SIVA1 TEX11 TRIM54 USHBP1
Entrez ID		54556
HPRD ID		06321
Ensembl ID		ENSG00000071243
Uniprot IDs		B7ZKQ7 Q9NXR8
PDB IDs		1X4I 7ZMX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type II Interferon-mediated Signaling Pathway Negative Regulation Of Pinocytosis Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Negative Regulation Of Cholesterol Storage Negative Regulation Of Macrophage Derived Foam Cell Differentiation Phosphatidylcholine Acyl-chain Remodeling Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Lipid Storage Positive Regulation Of Triglyceride Metabolic Process Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of Cholesterol Efflux Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Transport Negative Regulation Of Lipid Transport Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Lipid Storage Regulation Of Fatty Acid Biosynthetic Process MRNA Transcription By RNA Polymerase II Regulation Of Cholesterol Efflux Negative Regulation Of Cold-induced Thermogenesis Negative Regulation Of Response To Endoplasmic Reticulum Stress Nuclear Receptor Activity Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway MRNA Transcription Positive Regulation Of Secretion Of Lysosomal Enzymes Negative Regulation Of Secretion Of Lysosomal Enzymes CD27 Receptor Binding Meiotic Gene Conversion Putamen Development Caudate Nucleus Development Phosphatidylcholine Metabolic Process Regulation Of Endocytosis Regulation Of Cholesterol Transport Negative Regulation Of Endocytosis Regulation Of Small Molecule Metabolic Process Regulation Of MiRNA Transcription Positive Regulation Of Transport Acetylcholine Receptor Activator Activity Regulation Of MiRNA Metabolic Process Metal Ion Binding Regulation Of Proteolysis
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