ING3

Gene Name		inhibitor of growth family, member 3
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Gene Ontology Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Histone Acetyltransferase Activity Zinc Ion Binding Methylated Histone Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Growth Positive Regulation Of Apoptotic Process Histone H4 Acetylation Histone H2A Acetylation
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: APP FBXO25 NR1H2 NR1H3 TEX11 TRIM54 USHBP1
Entrez ID		54556
HPRD ID		06321
Ensembl ID		ENSG00000071243
Uniprot IDs		Q9NXR8
PDB IDs		1X4I
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Pinocytosis Negative Regulation Of Cholesterol Storage Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Cholesterol Homeostasis Positive Regulation Of Cholesterol Efflux Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Lipoprotein Lipase Activity Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Cholesterol Transport Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage Regulation Of Cholesterol Efflux Regulation Of Triglyceride Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Negative Regulation Of Lipid Transport Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Cholesterol Transport Regulation Of Triglyceride Metabolic Process Negative Regulation Of Innate Immune Response Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Endocytosis Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Lipid Storage Positive Regulation Of Lipid Transport Regulation Of Protein Processing Positive Regulation Of Lipid Biosynthetic Process Cholesterol Homeostasis Sterol Homeostasis Regulation Of Cellular Ketone Metabolic Process Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Lipase Activity Regulation Of Lipid Transport Steroid Hormone Mediated Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Secretion Of Lysosomal Enzymes Negative Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Lipid Homeostasis Regulation Of Proteolysis Negative Regulation Of Immune Response Hormone-mediated Signaling Pathway Regulation Of Lipid Biosynthetic Process Synaptic Growth At Neuromuscular Junction
Tagcloud ?		adenocarcinoma adenoma carcinogenesis clinicopathological colo201 colo205 colorectal depth dld downregulated forming hct ht immunohistochemically interpretation invasion kaplan km lymphatic meier mucosa neoplastic nnm node staging sw480 sw620 venous widr