ATR and LIG4

  • Number of citations of the paper that reports this interaction (PMID 10608806)
  • 171
  • Data Source:
  • BioGRID (unspecified method)

ATR

LIG4

Gene Name ATR serine/threonine kinase ligase IV, DNA, ATP-dependent
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions 47 interactors: AATF ABL1 AP1B1 AP2A2 ARHGEF1 ATM ATRIP BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CLSPN CREB1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 FANCA FANCD2 FLT1 H2AFX KDR LIG4 MCM2 MRE11A MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R2A PTS RAD17 RHEB TP53 TREX1 UPF1 VPRBP XPA XRCC5 103 interactors: ACTG1 AFTPH AGAP4 ALMS1 AMZ2P1 ANAPC10 APLF ASPM ATM ATP6V0D1 ATR B9D1 CAP1 CCDC176 CLU COL1A2 COMMD1 COX1 COX2 COX3 CPNE1 CREBBP CTSK DDX19A DGUOK DPP3 EIF2AK1 EIF3I EIF4A1 EIF4G3 ENO1 ETF1 FAM214A FBLL1 FIP1L1 GAPDH GGH GPANK1 GRHPR GUSBP3 GZMK HMGN1 HNRNPA2B1 IPP KDELR1 KIF3A LAP3 MAP2K2 MCM4 MCRS1 MRPS18C ND1 ND4 ND5 NDUFA13 NDUFB10 NEU1 NHEJ1 NOMO3 NPC2 OGFOD1 OSTM1 OXR1 PA2G4 PALLD PEX10 PGP PHF10 PMS2P1 PPIA PRKDC PSMA6 RBM5 RHBDD2 RPL11 RPS19BP1 RUVBL2 SEMA4G SMC2 SNX3 SOWAHC SRSF2 SYCP3 THOC5 TLE4 TOP1 TP53BP1 TPT1 TRAPPC3 TSFM UBB UBE2L3 UFSP2 UNC119 VKORC1 WARS WBP1L WDR20 XRCC4 ZFAND2A ZNF428 ZSCAN18 ZWINT
Entrez ID 545 3981
HPRD ID 08369 03500
Ensembl ID ENSG00000175054 ENSG00000174405
Uniprot IDs Q13535 P49917
PDB IDs 1IK9 2E2W 3II6 3VNN 3W1B 3W1G 3W5O 4HTO 4HTP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Difference) ?
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Intersection) ?