LIG4 and SRSF2

  • Number of citations of the paper that reports this interaction (PMID 22990118)
  • 7
  • Data Source:
  • BioGRID (two hybrid)

LIG4

SRSF2

Gene Name ligase IV, DNA, ATP-dependent serine/arginine-rich splicing factor 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions 103 interactors: ACTG1 AFTPH AGAP4 ALMS1 AMZ2P1 ANAPC10 APLF ASPM ATM ATP6V0D1 ATR B9D1 CAP1 CCDC176 CLU COL1A2 COMMD1 COX1 COX2 COX3 CPNE1 CREBBP CTSK DDX19A DGUOK DPP3 EIF2AK1 EIF3I EIF4A1 EIF4G3 ENO1 ETF1 FAM214A FBLL1 FIP1L1 GAPDH GGH GPANK1 GRHPR GUSBP3 GZMK HMGN1 HNRNPA2B1 IPP KDELR1 KIF3A LAP3 MAP2K2 MCM4 MCRS1 MRPS18C ND1 ND4 ND5 NDUFA13 NDUFB10 NEU1 NHEJ1 NOMO3 NPC2 OGFOD1 OSTM1 OXR1 PA2G4 PALLD PEX10 PGP PHF10 PMS2P1 PPIA PRKDC PSMA6 RBM5 RHBDD2 RPL11 RPS19BP1 RUVBL2 SEMA4G SMC2 SNX3 SOWAHC SRSF2 SYCP3 THOC5 TLE4 TOP1 TP53BP1 TPT1 TRAPPC3 TSFM UBB UBE2L3 UFSP2 UNC119 VKORC1 WARS WBP1L WDR20 XRCC4 ZFAND2A ZNF428 ZSCAN18 ZWINT 33 interactors: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRSF1 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID 3981 6427
HPRD ID 03500 02888
Ensembl ID ENSG00000174405 ENSG00000161547
Uniprot IDs P49917 Q01130 Q53FN0
PDB IDs 1IK9 2E2W 3II6 3VNN 3W1B 3W1G 3W5O 4HTO 4HTP 2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
asxl1  biologic  clonal  cmml  created  cytopenias  dependence  discern  dysplasia  entity  extramedullary  extrapolation  focuses  granulocyte  hematologic  identifies  landscape  macrophage  makes  malignancy  monocytosis  myelomonocytic  ontology  propensity  scientific  speculative  supporting  tools  troublesome 
Tagcloud (Difference) ?
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  mechanistically  nhej  overhang  parp1  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
asxl1  biologic  clonal  cmml  created  cytopenias  dependence  discern  dysplasia  entity  extramedullary  extrapolation  focuses  granulocyte  hematologic  identifies  landscape  macrophage  makes  malignancy  monocytosis  myelomonocytic  ontology  propensity  scientific  speculative  supporting  tools  troublesome 
Tagcloud (Intersection) ?