ATR and PIK3CA

  • Number of citations of the paper that reports this interaction (PMID 10608806)
  • 171
  • Data Source:
  • BioGRID (unspecified method)

ATR

PIK3CA

Gene Name ATR serine/threonine kinase phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AATF ABL1 AP1B1 AP2A2 ARHGEF1 ATM ATRIP BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CLSPN CREB1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 FANCA FANCD2 FLT1 H2AFX KDR LIG4 MCM2 MRE11A MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R2A PTS RAD17 RHEB TP53 TREX1 UPF1 VPRBP XPA XRCC5 43 interactors: ADAP1 AMBP APLP2 APPL1 ATPIF1 ATR DDX5 DNAJB6 FASLG FTL GABRB1 GNAQ GRIN2B HRAS IL3 IRS2 IRS4 ITIH1 KRAS LCK MRAS NEDD9 NRAS PDE4D PDGFRB PIK3R1 PIK3R3 PRKCD RASD2 RASGRP3 RPS20 RPS6KB1 SGK1 SH3KBP1 SLC9A3R1 SLC9A3R2 SMAD2 SMAD3 SQSTM1 STAT1 TICAM1 UFD1L VARS2
Entrez ID 545 5290
HPRD ID 08369 01382
Ensembl ID ENSG00000175054
Uniprot IDs Q13535 P42336
PDB IDs 2ENQ 2RD0 3HHM 3HIZ 3ZIM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
Tagcloud (Difference) ?
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
Tagcloud (Intersection) ?